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1.
J Indian Soc Periodontol ; 26(1): 13-18, 2022.
Article in English | MEDLINE | ID: mdl-35136311

ABSTRACT

BACKGROUND AND OBJECTIVES: Periodontitis caused by multifactorial polymicrobial infection results in a destructive inflammatory process and loss of tooth supporting tissues. Many putative bacterial virulence factors that cause host destruction are regulated by iron and haem. Therefore, this study investigated the free haem levels in the gingival crevicular fluid (GCF) at periodontitis sites in smokers and nonsmokers and their relationship to subgingival microbial composition. MATERIALS AND METHODS: A cross-sectional study was carried out on 78 patients with a split-mouth design who were divided into Group I A - periodontally healthy sites and Group I B - periodontally diseased sites in nonsmokers with chronic periodontitis and Group II A - periodontally healthy sites and Group II B - periodontally diseased sites in smokers. Clinical parameters recorded included a plaque and gingival index, papillary bleeding index, pocket probing depth, and clinical attachment level. The collected GCF samples were subjected to Biovision™ Hemin Colorimetric Assay Kit and subgingival plaque samples to BANA™ test. RESULTS: Increased GCF free haem concentration and positive BANA sites were seen at periodontitis sites compared to healthy sites, in both smokers and nonsmokers group. However, no difference was found in GCF free haem levels between smokers and nonsmokers, but it was statistically significant with respect to BANA-positive sites. CONCLUSION: Thus, this study concludes that the higher concentration of GCF free haem at diseased sites indicates that it could be used as a potential biomarker to determine active periodontal sites, also smoking and BANA results did not influence the biomarker levels.

2.
J Pharm Bioallied Sci ; 11(Suppl 1): S24-S29, 2019 Feb.
Article in English | MEDLINE | ID: mdl-30923427

ABSTRACT

AIM: The aim of the research was to develop a model that accurately represents an Aramany class I defect and its obturator prostheses fabricated with cobalt-chromium alloy and titanium alloy to compare the deflection and the stress distribution in the rehabilitated area. MATERIALS AND METHODS: Aramany class I defect and the obturator prostheses were generated geometrically using ANSYS 14.5; both were superimposed on each other to mimic the prostheses and the maxilla as one unit. Meshing of models was carried out using hypermesh software and materialistic properties were assigned. The 120 newton load was constituted on the teeth in different directions. STATISTICAL ANALYSIS USED: Statistical analysis of Finite element was not possible. Self-explanatory decoding results in the software were used. RESULTS: The stress distribution and deflection executed by ANSYS provided results that enabled the tracing of Von Mises stress and deflection field in the form of color-coded bands with values in mega pascal. CONCLUSIONS: The study shows that Von Mises stresses are higher for the frame work fabricated with cobalt-chromium alloy compared to titanium alloy. The framework made of titanium alloy showed more deflection than cobalt-chromium alloy.

3.
J Pharm Bioallied Sci ; 11(Suppl 1): S72-S75, 2019 Feb.
Article in English | MEDLINE | ID: mdl-30923434

ABSTRACT

It is fairly common to remove a severely compromised tooth and provide rehabilitation by means of an implant. Resorption of alveolar bone after extraction resulting in loss of bone height and width is an unpleasant sequelae causing difficulty in implant placement. Few procedures have been promoted to attain the required bone height and width, such as guided bone regeneration socket preservation with the use of various graft materials and barrier membranes. The disadvantages of these techniques are some amount of ridge height loss and loss of buccal/facial, ridge contour. The socket shield technique is a new method where a buccal segment of root is retained as a shield, which aids in retaining periodontal ligament on buccofacial aspect. The implant is placed (immediate placement) lingual to this shield. This maintains the alveolar ridge height and buccofacial contour, thus providing superior aesthetics. This case report shows placement of an implant in upper anterior region using this technique.

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