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Biull Eksp Biol Med ; 100(8): 245-7, 1985 Aug.
Article in Russian | MEDLINE | ID: mdl-3161560

ABSTRACT

It has been established in experiments on 280 white randombred male rats weighing 100-120 g that the lifting of the animals from the valley (820 m above the sea level) to the mountains (3379 m above the sea level) brings about within the first day marked suppression of the mitotic activity of the epithelium of involuted renal tubules. This activity increases beginning from the end of the first week, approaches the control value by the 30th day of adaptation and almost completely returns to normal by the 60th day of the animals' stay in the mountains. The circadian rhythms of the mitotic activity appeared undisturbed and was monophasic in nature.


Subject(s)
Adaptation, Physiological , Altitude , Circadian Rhythm , Kidney Tubules/cytology , Mitosis , Animals , Epithelial Cells , Male , Rats , Tajikistan , Time Factors
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