Addressing the Challenge of Biomedical Data Inequality: An Artificial Intelligence Perspective.

Artificial intelligence (AI) and other data-driven technologies hold great promise to transform healthcare and confer the predictive power essential to precision medicine. However, the existing biomedical data, which are a vital resource and foundation for developing medical AI models, do not reflect the diversity of the human population. The low representation in biomedical data has become a significant health risk for non-European populations, and the growing application of AI opens a new pathway for this health risk to manifest and amplify. Here we review the current status of biomedical data inequality and present a conceptual framework for understanding its impacts on machine learning. We also discuss the recent advances in algorithmic interventions for mitigating health disparities arising from biomedical data inequality. Finally, we briefly discuss the newly identified disparity in data quality among ethnic groups and its potential impacts on machine learning.

Two-Dimensional Permutation Vectors' (PV) Code for Optical Code Division Multiple Access Systems.

In this paper, we present a new algorithm to generate two-dimensional (2D) permutation vectors' (PV) code for incoherent optical code division multiple access (OCDMA) system to suppress multiple access interference (MAI) and system complexity. The proposed code design approach is based on wavelength-hopping time-spreading (WHTS) technique for code generation. All possible combinations of PV code sets were attained by employing all permutations of the vectors with repetition of each vector weight (W) times. Further, 2D-PV code set was constructed by combining two code sequences of the 1D-PV code. The transmitter-receiver architecture of 2D-PV code-based WHTS OCDMA system is presented. Results indicated that the 2D-PV code provides increased cardinality by eliminating phase-induced intensity noise (PIIN) effects and multiple user data can be transmitted with minimum likelihood of interference. Simulation results validated the proposed system for an agreeable bit error rate (BER) of 10-9.