ABSTRACT
A 47 years old man had 13 episodes of relapsing and remitting sensory-motor neuropathy involving the upper limbs over the last 20 years. All but the last episode resolved spontaneously within 2 months. Neurophysiology revealed multifocal motor and sensory conduction block in the upper limbs with normal terminal latencies. CSF analysis was normal and anti-GM1 antibodies were not detected. There was a dramatic clinical improvement after intravenous immunoglobulin treatment. This case represents an unusual multifocal variant of chronic inflammatory demyelinating neuropathy.
Subject(s)
Motor Neurons/physiology , Neural Conduction , Neurons, Afferent/physiology , Polyradiculoneuropathy, Chronic Inflammatory Demyelinating/physiopathology , Action Potentials , Chronic Disease , Extremities/innervation , Humans , Immunoglobulins, Intravenous/therapeutic use , Male , Middle Aged , Muscle, Skeletal/physiopathology , Polyradiculoneuropathy, Chronic Inflammatory Demyelinating/therapy , Recurrence , Treatment OutcomeSubject(s)
Anticonvulsants/adverse effects , Epilepsy, Absence/chemically induced , gamma-Aminobutyric Acid/analogs & derivatives , Adult , Electroencephalography , Epilepsy, Absence/physiopathology , Epilepsy, Generalized/drug therapy , Humans , Male , Middle Aged , Vigabatrin , gamma-Aminobutyric Acid/adverse effectsABSTRACT
Three cases are reported in which symptoms of occipital seizures resembled the visual aura of migraine. Careful recording of the characteristics and timing of such visual effects will often resolve the diagnostic dilemma.
