ABSTRACT
AIM: To examine factors and determinants of ocular neurovascular reactions (NVR). MATERIAL AND METHODS: The study included 120 healthy participants of both sexes aged 20.9±0.6 years, who underwent a standard ophthalmic examination. Ocular microcirculation was recorded using laser Doppler flowmetry. Autonomic homeostasis and the intensity of slow-wave oscillations of hemodynamics were of interest. Autoregulation of cerebral blood flow was assessed by transcranial color-coded duplex scanning. RESULTS: The dynamics of perfusion control mechanisms (myogenic and neurogenic) have been studied in the young healthy population of Krasnoyarsk. The role of the autonomic nervous system in initiating a particular type of ocular NVR has been identified. The authors have also determined the significance of the nitric oxide production intensity in different types of NVR. CONCLUSION: The type of ocular NVR is determined by parameters of cerebral hemodynamics. Normotonic NVR is associated with effective autoregulation of cerebral blood flow, while hyper- and hypotonic types of reactions - with autoregulatory failure.
Subject(s)
Brain/blood supply , Eye , Microcirculation/physiology , Neurovascular Coupling/physiology , Autonomic Nervous System/physiology , Eye/blood supply , Eye/innervation , Female , Healthy Volunteers , Homeostasis/physiology , Humans , Laser-Doppler Flowmetry/methods , Male , Nitric Oxide/metabolism , Oscillometry/methods , Ultrasonography, Doppler, Transcranial/methods , Young AdultABSTRACT
The authors present their experience gained in the training of ophthalmologists at the Chair of Ocular Diseases of the Krasnoyarsk Medical Institute. In 1991 the interns, instead of traditional state examinations, maintained their diploma research, which was assessed as their skills and knowledge in the field of ocular diseases, social hygiene, and public health organization. The authors prove that such diploma research is an integral part of undergraduate training and one of the types of individual work at higher educational institutions, and enumerate the topics of diploma research.
