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Sud Med Ekspert ; 52(5): 37-40, 2009.
Article in Russian | MEDLINE | ID: mdl-20058850

ABSTRACT

Lethal concentration of bupivacaine was determined based on the examination of a case of poisoning with this local anesthetic agent taken at a dose 5 times the normal value. This study is of special interest taking into consideration the lack of data on toxic and lethal doses of bupivacaine in splanchnic organs and tissues in the literature.


Subject(s)
Anesthetics, Local/poisoning , Bupivacaine/poisoning , Forensic Toxicology , Medication Errors , Anesthetics, Local/administration & dosage , Anesthetics, Local/isolation & purification , Anesthetics, Local/pharmacokinetics , Anesthetics, Local/therapeutic use , Bupivacaine/administration & dosage , Bupivacaine/isolation & purification , Bupivacaine/pharmacokinetics , Bupivacaine/therapeutic use , Fatal Outcome , Humans , Male , Organ Specificity , Poisoning/diagnosis , Tissue Distribution
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