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1.
Circulation ; 148(23): 1847-1856, 2023 12 05.
Article in English | MEDLINE | ID: mdl-37952192

ABSTRACT

BACKGROUND: Few studies have measured ventilation during early cardiopulmonary resuscitation (CPR) before advanced airway placement. Resuscitation guidelines recommend pauses after every 30 chest compressions to deliver ventilations. The effectiveness of bag-valve-mask ventilation delivered during the pause in chest compressions is unknown. We sought to determine: (1) the incidence of lung inflation with bag-valve-mask ventilation during 30:2 CPR; and (2) the association of ventilation with outcomes after out-of-hospital cardiac arrest. METHODS: We studied patients with out-of-hospital cardiac arrest from 6 sites of the Resuscitation Outcomes Consortium CCC study (Trial of Continuous Compressions versus Standard CPR in Patients with Out-of-Hospital Cardiac Arrest). We analyzed patients assigned to the 30:2 CPR arm with ≥2 minutes of thoracic bioimpedance signal recorded with a cardiac defibrillator/monitor. Detectable ventilation waveforms were defined as having a bioimpedance amplitude ≥0.5 Ω (corresponding to ≥250 mL VT) and a duration ≥1 s. We defined a chest compression pause as a 3- to 15-s break in chest compressions. We compared the incidence of ventilation and outcomes in 2 groups: patients with ventilation waveforms in <50% of pauses (group 1) versus those with waveforms in ≥50% of pauses (group 2). RESULTS: Among 1976 patients, the mean age was 65 years; 66% were male. From the start of chest compressions until advanced airway placement, mean±SD duration of 30:2 CPR was 9.8±4.9 minutes. During this period, we identified 26 861 pauses in chest compressions; 60% of patients had ventilation waveforms in <50% of pauses (group 1, n=1177), and 40% had waveforms in ≥50% of pauses (group 2, n=799). Group 1 had a median of 12 pauses and 2 ventilations per patient versus group 2, which had 12 pauses and 12 ventilations per patient. Group 2 had higher rates of prehospital return of spontaneous circulation (40.7% versus 25.2%; P<0.0001), survival to hospital discharge (13.5% versus 4.1%; P<0.0001), and survival with favorable neurological outcome (10.6% versus 2.4%; P<0.0001). These associations persisted after adjustment for confounders. CONCLUSIONS: In this study, lung inflation occurred infrequently with bag-valve-mask ventilation during 30:2 CPR. Lung inflation in ≥50% of pauses was associated with improved return of spontaneous circulation, survival, and survival with favorable neurological outcome.


Subject(s)
Cardiopulmonary Resuscitation , Out-of-Hospital Cardiac Arrest , Humans , Male , Aged , Female , Out-of-Hospital Cardiac Arrest/therapy , Respiration, Artificial/adverse effects , Pressure , Thorax
2.
J Geriatr Phys Ther ; 42(2): 86-97, 2019.
Article in English | MEDLINE | ID: mdl-28452837

ABSTRACT

BACKGROUND AND PURPOSE: A growing population of older adults will require health care professionals to become increasingly knowledgeable in geriatric care. Patient ratings, functional measures, and emphasis on health and wellness should be part of geriatric physical therapy practice. The purpose of the current study was to examine relationships between self-rated health (SRH) and movement-related variables in older adults using the International Classification of Functioning, Disability, and Health (ICF) as a research framework. Associations between body mass index (BMI), gait, and balance confidence were also explored. METHODS: Thirty older adults (mean age = 74.1 years; 18 women and 12 men) participated in the study and completed the following questionnaires: SRH, Short Activities-specific Balance Confidence scale, Keele Assessment of Participation, and the Neighborhood Environment Walkability Scale-Abbreviated. Spatiotemporal gait parameters, BMI, and isokinetic knee extensor strength were also assessed. RESULTS: Bivariate results indicated significant associations between SRH and double-support time during gait (rs = -0.6, P < .001), gait speed (rs = 0.4, P = .05), step length (rs = 0.4, P = .05), BMI (rs = -0.4, P = .015), and hilliness of neighborhood (rs = -0.4, P = .015). Individual regression models, controlling for education and age, demonstrated that double-support time was the strongest predictor of SRH (R = 0.50, P = .001). Comparisons of the low versus high BMI groups indicated more favorable balance confidence and gait characteristics for the low BMI group, particularly in double support (t = -3.8, P = .001). CONCLUSIONS: SRH should be considered as a quick, patient-focused assessment of health in older adults. Measures of double-support time and BMI may provide clinicians with useful information about their geriatric patients' overall health and function.


Subject(s)
Gait , Health Status , Surveys and Questionnaires , Aged , Aged, 80 and over , Body Mass Index , Exercise Test , Female , Humans , International Classification of Functioning, Disability and Health , Male , Muscle Strength , Postural Balance , Quadriceps Muscle/physiology , Walking Speed
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