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Suspected opioid overdose case resolved by CYP2D6 genotyping.
Shaw, Kaitlyn D; Amstutz, Ursula; Jimenez-Mendez, Ricardo; Ross, Colin J D; Carleton, Bruce C.
Ther Drug Monit ; 34(2): 121-3, 2012 Apr.
Article in English | MEDLINE | ID: mdl-22406651

ABSTRACT

A 14-year-old female with suspected narcotic overdose had CYP2D6 genotyping performed to verify opiate intoxication. The role of pharmacogenetics in pain management and individualization of opiate pharmacotherapy is discussed.


Subject(s)
Analgesics, Opioid/adverse effects , Codeine/adverse effects , Cytochrome P-450 CYP2D6/genetics , Acetaminophen/administration & dosage , Adolescent , Analgesics, Opioid/administration & dosage , Analgesics, Opioid/metabolism , Caffeine/administration & dosage , Codeine/administration & dosage , Codeine/metabolism , Drug Combinations , Drug Overdose , Female , Genotype , Humans , Pain/drug therapy , Pharmacogenetics
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