[The effect of diet with an increased amount of tyrosine on reparative processes in the duodenum]. / Vliianie ratsiona s povyshennym kolichestvom tirozina na reparativnye protsessy v dvenadtsatiperstnoi kishke.

It has been shown that the development of destructive lesions of the duodenal wall induced by stress action on the body of the experimental animal is attended by a decrease of the content of creatine phosphate and noradrenaline in homogenate of the duodenal tissue. The use of tyrosine, a precursor of catecholamine biosynthesis, both as a pharmacologic agent and as a component of rich in this amino-acid product-dried milk, resulted in normalization of the biochemical parameters studied and in significant diminution of destructive lesions of the duodenal wall.

[Enterosorption in chronic enterocolitis]. / Enterosorbtsiia pri khronicheskom énterokolite.

Polyfepan, a sorbent, included in the complex of therapeutic measures for the patients with exacerbations of chronic enterocolitis, has considerably reduced the terms necessary to arrest the major symptoms of the condition vs. the reference group. The effect was the most manifest when the sorbent was combined with polyenzyme drugs. Laboratory tests and rat experiments have helped validate polyfepan action as the agent binding microorganisms and their toxins on its surface and fixing the enzyme vector at the site of the pathologic process.

[Effect of a diet with an increased protein content on reparative processes in experimental ulcerous lesions of the gastric and duodenal mucosa]. / Vliianie diety s povyshennym soderzhaniem belka na reparativnye protsessy pri eksperimental'nykh iazvennykh porazheniiakh slizistoi obolochki zheludka i dvenadtsatiperstnoi kishki.

Experimental rats were subjected to an extreme action: 3-hour immobilization with simultaneous electrostimulation. A complete healing of erosion-ulcerous defects of the gastroduodenal mucosa was recorded in rats given diets with an increased (by 4 g) protein content (group I), on day 5. The mucosal affections in the rats receiving a standard ration still persisted. The content of creatine-phosphate in the gastric wall tissue, decreased under the extreme action, was rapidly recovered in group I rats, no changes in the proper fluorescence level of reduced NADH and flavoproteins were noted. In group II rats both parameters returned to normal only on day 5. Blood serum ceruloplasmin (CP) activity increased during first 3 days with a similar rate in both animal groups. However, in the following 2 days CP activity in group I rats became completely normal, while that in group II animals was still rising. The results of the study have shown that the diet with increased protein content stimulates epithelization of the gastroduodenal mucosa due to the improvement of the bioenergy processes in the gastroduodenal area, and to intensified adaptation potentialities of the body.