1.
Med Tr Prom Ekol
; (8): 15-8, 1997.
Article
in Russian
| MEDLINE
| ID: mdl-9377047
ABSTRACT
The article presents studies of hormonal state in rats under daily or 20-day peroral administration of variable doses of 2,4-D herbicide containing dioxine. Changed levels of thyroid hormones, insulin, cortisol, testosterone and estradiol appeared to be divergent and dose-dependent, proving direct toxic effects of the herbicide in endocrine organs, altered hormonal effects in target organs and disorders of peripheral hormonal metabolism.