[The Lewis antigen system as a marker of IHD risk]. / Sistema antigenov Lewis kak marker riska IBS.

Prevalence of Lewis antigens and phenotypes has been investigated in 60 healthy donors and 74 patients with ischemic heart disease. It was found that phenotype Le(a-b-) marks high risk and phenotype Le(a-b+) is a resistance marker for development of ischemic heart disease. It would be valid to elucidate relationships between Lewis system and pathogenesis of internal diseases.

[The possibilities for the pathogenetic therapy of ischemic heart disease under cardioselective loading]. / Vozmozhnosti patogeneticheskoi terapii ishemicheskoi bolezni serdtsa v usloviiakh kardioselektivnoi nagruzki.

The authors describe the method for the treatment of ischemic heart disease (IHD) with stenocardia at rest or tension which is refractory for basic therapy. This method consists of intravenous injection of phosphobion on the background of transesophageal electrocardiostimulation. Anti-ischemic and positive hemodynamic effects were marked during application of this method in 16 patients with IHD. On the contrary the traditional method based on administration of adesinotriphosphorous acid didn't give positive clinical results.

[Therapeutic effect of intravascular phosphobion during transesophageal electric cardiostimulation in patients with ischemic heart disease]. / Lechebnyi éffect vnutrivennogo vvedeniia fosfobiona pri chrespishchevodnoi élektrokardiostimuliatsii u bolnykh ishemicheskoi bolezníu serdtsa.

The authors propose a new method of treating coronary patients with angina pectoris of effort and at rest. It involves combination of transesophageal pacing with simultaneous intravenous administration of phosphobion. The treatment given to 10 coronary patients produced positive antiischemic and hemodynamic effect against its absence in control subjects treated conventionally with ATP.