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1.
Med Tr Prom Ekol ; (6): 6-10, 2000.
Article in Russian | MEDLINE | ID: mdl-10934847

ABSTRACT

Chronic dust bronchitis in miners is associated with increase in dynamic surface tension of blood at short (t = 0.01 s) and medium (t = 1 s) surface lifetimes with lower declination angle of interphase tensiograms curve. Surface tension disorders were similar to those in experimental dust bronchitis. There are correlations between surface tension parameters and the workers' underground length of service, some mining geologic conditions and serum level of proteous and lipid surfactants.


Subject(s)
Bronchitis/etiology , Coal Mining , Dust/adverse effects , Occupational Diseases/etiology , Adult , Aged , Chronic Disease , Hemodynamics , Humans , Male , Middle Aged
2.
Med Tr Prom Ekol ; (10): 21-5, 1999.
Article in Russian | MEDLINE | ID: mdl-10568314

ABSTRACT

The disease was simulated by inhalation of dust containing 29% of free silica in Wistar male rats during 8 months. One group of the subjects was kept under 26-28 degrees C and other one--under 38-40 degrees C. Dynamic surface tension of lung tissue homogenate was studied by means of computer tensiometer MRT (Lauda, Germany). Interphase tensiometry precisely characterizes state of lung surfactant in experimental chronic dust bronchitis. Equilibrium surface tension and surface tension for 0.01 and 1 sec deteriorate during combined exposure to silica dust and heating microclimate. The studies demonstrated strong correlation between interphase tensiogram parameters and individual lipids content of lung surfactant. Surface tension is related to the state of lipids peroxidation in lungs and antioxidant systems.


Subject(s)
Bronchitis/physiopathology , Dust/adverse effects , Pulmonary Surfactants/physiology , Silicon Dioxide/adverse effects , Animals , Bronchitis/etiology , Chronic Disease , Disease Models, Animal , Lipid Peroxidation/physiology , Lung/physiopathology , Male , Rats , Rats, Wistar , Surface Tension , Temperature
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