ABSTRACT
Time-temperature dependence of concentrations of outgasing products of polymers and rubbers was studied. Applying the principle of time-temperature equilibrium, the exposure time for a laboratory rapid study of polymers at 100 degrees C was estimated to be 1 hr for enamels, lacquers and dyes, 1.5 hr for block and sheet polymers, 2.5 hr for sealants and rubbers, and 4 hr for textile materials, measured from the time when the preassigned temperature was achieved. The rapid method can be recommended for preliminary chemical study of polymers at the stage of their laboratory testing.
Subject(s)
Gases/analysis , Plastics/analysis , Rubber/analysis , Temperature , Construction Materials , Diffusion , Dose-Response Relationship, Drug , Drug Stability , Time Factors , VolatilizationABSTRACT
Experiments were carried out to study the resistance of rats to an acute effect of ethylacetate vapors at concentrations of 25 to 69 g/m-3 after their 20-day exposure to hypokinesia and 20-day exposure to altitudes of 3200 and 5000 m. The effect of ethylacetate at concentrations of 47 and 10 mg/m-3 on the rats in a chronic 90-day experiments was also investigated. After an exposure to hypokinesia and hypoxia the sensitivity of the rats to an acute effect of ethylacetate vapors increased 2- or 3-fold. The chronic inhalation of the substance by the hypokinetic animals brought about disorders in the brain microstructure and renal pathology. The poisoned animals that retained normal motor activity displayed serious pathological changes in the thyroid gland. It is concluded that changes in the reactivity of the animal and human body to chemical agents must be taken into consideration when developing standards for the space cabin atmosphere.