ABSTRACT
An evaluation was done in 172 patients with progressive stenocardia. The use of intracardiac laser light irradiation of blood in combined treatment was found to improve the clinical course of the illness and to have a beneficial effect on the factors of plasma haemostasis and fibrinolysis which play a pathogenetic role in the destabilization of the ischemic heart disease course, this being manifest by a significant decrease in the activity of factor XIII, platelet factor 4, and an increase in fibrinolysis.
Subject(s)
Angina, Unstable/therapy , Blood Transfusion, Autologous/methods , Blood/radiation effects , Fibrinolysis/radiation effects , Hemostasis/radiation effects , Laser Therapy , Plasma/radiation effects , Ultraviolet Therapy/methods , Angina, Unstable/blood , Combined Modality Therapy , Humans , Male , Middle AgedABSTRACT
Coronary reserve and functional state of myocardium were studied in 27 patients with unstable angina and myocardial infarction which had developed in spite of the treatment. Non-invasive study included stress-tests (transesophageal electrocardiostimulation, bicycle ergometry [correction of veloergometry)], echocardiography and Holter's monitoring. Possibility of early forming of risk group with consequent optimization of the treatment was shown.
Subject(s)
Angina, Unstable/complications , Myocardial Infarction/etiology , Angina, Unstable/diagnosis , Heart Function Tests , Humans , Male , Middle Aged , Myocardial Infarction/diagnosis , Myocardial Infarction/epidemiology , Probability , Prognosis , Risk FactorsABSTRACT
Procedures, connected with extracorporal blood circulation--hemodialysis, hemosorption and plasmapheresis--were used in complex of treatment in 30 patients with various cardiovascular diseases. As an anticoagulant in 8 patients was used the preparation of low molecular heparine (Fraxiparine) produced by "Sanofi" (France) firm, and in 22-heparin, produced by "Polfa" (Poland). Ascertained advantages of Fraxiparine versus heparin were: possibility of single injection of preparation, the reducing of total dose magnitude, which is needed for one curative act conduction, lowering by 70% approximately the hemorrhagic complications rate.
Subject(s)
Anticoagulants/therapeutic use , Cardiovascular Diseases/therapy , Nadroparin/therapeutic use , Sorption Detoxification/methods , Anticoagulants/adverse effects , Cardiovascular Diseases/complications , Combined Modality Therapy , Drug Evaluation , Heparin/therapeutic use , Humans , Nadroparin/adverse effectsABSTRACT
Risk of sudden coronary death in patients with unstable stenocardia is studied insufficiently. 39 patients with unstable stenocardia underwent Holter's monitoring, loading tests and invasive programmed ventricular stimulation coming lately into increasingly wide use for assessment of myocardial electric stability. Programmed stimulation allowed to single out two groups of patients: with ventricular tachycardia (56.4%) and without it (43.6%). Results obtained by aforementioned methods showed no correlation which is explained by the authors as being due to different pathogenetical mechanisms initiating ventricular arrhythmias. Thus, for example, rhythm disorders emerged not infrequently in the periods of ischemia during Holter's monitoring while myocardial ischemia was not observed in all cases of programmed ventricular stimulation. That is why complex approach needs to be pursued for assessment of electric stability of myocardium in patients with advancing stenocardia.
Subject(s)
Heart/physiopathology , Myocardial Ischemia/physiopathology , Cardiac Complexes, Premature/diagnosis , Cardiac Complexes, Premature/physiopathology , Cardiac Pacing, Artificial , Electrocardiography, Ambulatory/instrumentation , Electrocardiography, Ambulatory/methods , Electrophysiology , Esophagus , Exercise Test , Heart Ventricles/physiopathology , Humans , Middle Aged , Myocardial Ischemia/diagnosis , Tachycardia, Ventricular/diagnosis , Tachycardia, Ventricular/physiopathologyABSTRACT
Effect of autohemotransfusions of ultraviolet-irradiated blood (UVIB) on ventricular arrhythmias and electric stability of myocardium were studied in 85 patients with advancing stenocardia. Bicycle ergometry [correction of Veloergometry], Holter's monitoring and invasive programmed cardiostimulation were used. Results of examination carried out before and after the treatment suggest anti-ischemic effect of PVIB and beneficial influence electrophysiological properties of myocardium which manifested in reduced periods of ventricular tachycardia and onsets of twin extrasystoles.
Subject(s)
Angina Pectoris/therapy , Blood Transfusion, Autologous , Blood/radiation effects , Ultraviolet Therapy , Adult , Aged , Angina Pectoris/diagnosis , Combined Modality Therapy , Humans , Middle Aged , PrognosisABSTRACT
Results are reported of an examination of 81 patients with acute macrofocal myocardial infarction. Routine methods of treatment were supplemented by laser and ultraviolet radiation of the blood. This treatment was highly effective in rapid control of stenocardia pain, early stabilization of the ST segment. The proposed treatment is recommended in patients with acute myocardial infarction.
