The diagnostic value of anthropometric indices of maxillary sinuses for sex determination using CT-scan images in Iranian adults: A cross-sectional study.

BACKGROUND: The identification of human remains is an essential part of forensic science. Studying paranasal sinuses is very useful in identification of mutilated or burnt bodies from accidents such as plane crashes. We aimed to assess the diagnostic value of anthropometric indices of maxillary sinuses for sex determination using CT-scan images in Iranian adults. METHODS: CT-scan slices of 228 maxillary sinuses (from 144 men and 144 women) were studied. The maximum height, maximum anterior-posterior diameter, maximum width, and maximum distance between the sinuses were measured in both sexes. Our participants were divided into three age groups of 20-34, 35-49, and over 50 to compare the recorded measurements in different age groups. RESULTS: We found a significant difference between men and women regarding the maximum height, maximum width, maximum A-P diameter of sinuses and the maximum distance between the right and left maxillary sinuses in all of our participants. We also found that the highest accuracy for sex determination was related to the maximum distance between the sinuses (65.6%) and the lowest to the maximum width of the right sinus (56.2%). The most accurate identification resulted from assessing the maximum distance between the sinuses in the 20-34 age group (74.3%), the maximum anterior-posterior diameter of the sinuses in the 35-49 age group (62.8%) and the maximum height of the left sinus in the over 50 age group (65.7%). CONCLUSION: Regardless of age, according to our study the parameters of height, width, anterior-posterior diameter of sinuses and the maximum distance between the right and left maxillary sinuses are partially valuable for sex determination. The most accurate sex identification was examined in the 20-34 age group from studying the maximum distance between the sinuses. Especially in the over 50 age group, it is not enough to consider the sinus parameter for sex identification.

Comparison of Quantitative and Qualitative Dermatoglyphic Characteristics of Opium Addicts with Healthy Individuals.

BACKGROUND: Recreational drugs have a significant impact on the lives of drug users, their close families andfriends, as well as their society. Social, psychological, biological, and genetic factors could make a personmore prone to using recreational drugs. Finger and A-B ridges (dermatoglyphics) are formed during the firstand second trimesters of fetal development, under the influence of environmental and genetic factors. Theaim of our study was to investigate and evaluate a possible link between dermatoglyphics and opium usage. METHODS: The pattern of dermatoglyphics - finger and A-B prints - obtained from a group of opium users(121 patients) was compared to those obtained from a group of opium non-users (121 patients) from Birjand,Iran. The results were analyzed using chi-square, t and Mann-Whitney tests. FINDINGS: The results showed that although A-B ridges of palms and fingers in our study group were highercompared to the control group, there was no significant difference between these groups. The only significantdifference was the fingerprint patterns of the left ring finger in the study group, which lacked the arch patternand had less loop patterns. The dominant type of fingerprint in the left ring finger was the whorl. In ouropium user group, the arch and loop fingerprint patterns were heterogeneous and significantly different incomparison with the control group (P < 0.01). CONCLUSION: These findings suggest that a genetic factor may increase the predisposition to recreational drugusage. Further research is required to confirm this possible impact of genetic factors on the addiction process.

Comparison of UHPLC and HPLC in benzodiazepines analysis of postmortem samples: a case-control study.

The aim of this study was to compare system efficiency and analysis duration regarding the solvent consumption and system maintenance in high-pressure liquid chromatography (HPLC) and ultra high-pressure liquid chromatography (UHPLC). In a case-control study, standard solutions of 7 benzodiazepines (BZs) and 73 biological samples such as urine, tissue, stomach content, and bile that screened positive for BZs were analyzed by HPLC and UHPLC in laboratory of forensic toxicology during 2012 to 2013. HPLC analysis was performed using a Knauer by 100-5 C-18 column (250 mm × 4.6 mm) and Knauer photodiode array detector (PAD). UHPLC analysis was performed using Knauer PAD detector with cooling autosampler and Eurospher II 100-3 C-18 column (100 mm × 3 mm) and also 2 pumps. The mean retention time, standard deviation, flow rate, and repeatability of analytical results were compared by using 2 methods. Routine runtimes in HPLC and UHPLC took 40 and 15 minutes, respectively. Changes in mobile phase composition of the 2 methods were not required. Flow rate and solvent consumption in UHPLC decreased. Diazepam and flurazepam were detected more frequently in biological samples. In UHPLC, small particle size and short length of column cause effective separation of BZs in a very short time. Reduced flow rate, solvent consumption, and injection volume cause more efficiency and less analysis costs. Thus, in the detection of BZs, UHPLC is an accurate, sensitive, and fast method with less cost of analysis.