Getting older, getting better? Personal strivings and psychological maturity across the life span.

Measures of psychological maturity based on personal strivings (R. A. Emmons, 1989) were administered to 108 adults aged 17-82. On the basis of organismic-theoretical assumptions regarding maturity, age was hypothesized to be positively associated with K. M. Sheldon and T. Kasser's (1995, 1998) two goal-based measures of personality integration. E. Erikson's (1963) assumptions regarding maturity were the basis for the hypothesis that older people would tend to list more strivings concerning generativity and ego integrity and fewer strivings concerning identity and intimacy. Finally, on the basis of past research findings, maturity and age were hypothesized to be positively associated with subjective well-being. Results supported these hypotheses and also showed that measured maturity mediated the relationship between age and well-being. Thus, older individuals may indeed be more psychologically mature than younger people and may be happier as a result.

Why positive psychology is necessary.

The authors provide a definition of positive psychology and suggest that psychologists should try to cultivate a more appreciative perspective on human nature. Examples are given of a negative bias that seems to pervade much of theoretical psychology, which may limit psychologists' understanding of typical and successful human functioning. Finally, a preview of the articles in the special section is given.

Self-concordance, goal attainment, and the pursuit of happiness: can there be an upward spiral?

Two studies used the self-concordance model of healthy goal striving (K. M. Sheldon & A. J. Elliot, 1999) to examine the motivational processes by which people can increase their level of well-being during a period of time and then maintain the gain or perhaps increase it even further during the next period of time. In Study 1, entering freshmen with self-concordant motivation better attained their 1st-semester goals, which in turn predicted increased adjustment and greater self-concordance for the next semester's goals. Increased self-concordance in turn predicted even better goal attainment during the 2nd semester, which led to further increases in adjustment and to higher levels of ego development by the end of the year. Study 2 replicated the basic model in a 2-week study of short-term goals set in the laboratory. Limits of the model and implications for the question of how (and whether) happiness may be increased are discussed.

What is satisfying about satisfying events? Testing 10 candidate psychological needs.

Three studies compared 10 candidate psychological needs in an attempt to determine which are truly most fundamental for humans. Participants described "most satisfying events" within their lives and then rated the salience of each of the 10 candidate needs within these events. Supporting self-determination theory postulates (Ryan & Deci, 2000)--autonomy, competence, and relatedness, were consistently among the top 4 needs, in terms of both their salience and their association with event-related affect. Self-esteem was also important, whereas self-actualization or meaning, physical thriving, popularity or influence, and money-luxury were less important. This basic pattern emerged within three different time frames and within both U.S. and South Korean samples and also within a final study that asked, "What's unsatisfying about unsatisfying events?" Implications for hierarchical theories of needs are discussed.

A cross-cultural analysis of avoidance (relative to approach) personal goals.

The results from this research supported our primary hypothesis that the adoption of avoidance (relative to approach) personal goals varies as a function of individualism-collectivism (across representations of this distinction). Interdependent self-construals were positively related and independent self-construals were negatively related to adoption of avoidance goals (Study 1), Asian Americans adopted more avoidance goals than non-Asian Americans (Study 2), andpersonsfrom South Korea and Russia adopted more avoidance goals than those in the United States (Studies 3 and 4, respectively). Studies 3 and 4 investigated andfound supportfor our secondary hypothesis that avoidance personal goals are a negative predictor of subjective well-being in individualistic (the United States), but not collectivistic (South Korea and Russia), countries. The findings are discussed in terms of other approach-avoidance constructs and motivational processes.

Personal goals in social roles: divergences and convergences across roles and levels of analysis.

Most contemporary personal goal research aggregates across goals, perhaps masking important differences between goals. We assessed this risk by examining both similarities and differences between the goals that participants pursued in five important social roles. Previous relevant findings (Cantor, Norem, Niedenthal, Langston, & Brower, 1987) and self-determination theory (Deci & Ryan, 1985) were used to predict between-role differences in goal appraisal dimensions. Although theoretically meaningful differences were found across child, employee, romantic, friendship, and student goals, and also across within- and between-subject levels of analysis, all goals were essentially the same in one important way: Making longitudinal progress in them predicted positive change in accompanying role-circumstances and role-satisfaction (excepting friendship goals). This indicates that researchers do not necessarily lose information by aggregating, and affirms that goal-attainment is generally desirable.

Extrinsic value orientation and "the tragedy of the commons".

Two studies examined the effect of Extrinsic Value Orientation (Kasser & Ryan, 1993, 1996) upon harvesting strategies and personal profit within commons dilemmas, in which individual and group interests can be at odds. At an individual or within-group level of analysis, extrinsically oriented persons (who value money, fame, and popularity) harvested more than intrinsically oriented persons (who value self-acceptance, intimacy, and community). However, a counteracting group-level effect was found such that groups with a greater number of extrinsic members harvested less on average than did groups with more intrinsic members, because their commons did not last as long. As a result, even excessive harvesters within extrinsic groups did no better than did self-restrained harvesters within intrinsic groups. Supplementary analyses indicate that extrinsic values are associated with acquisitiveness regarding resources, more so than apprehension regarding others' acquisitiveness.

Of wealth and death: materialism, mortality salience, and consumption behavior.

Theoretical work suggests that feelings of insecurity produce materialistic behavior, but most empirical evidence is correlational in nature. We therefore experimentally activated feelings of insecurity by having some subjects write short essays about death (mortality-salience condition). In Study 1, subjects in the mortality-salience condition, compared with subjects who wrote about a neutral topic, had higher financial expectations for themselves 15 years in the future, in terms of both their overall worth and the amount they would be spending on pleasurable items such as clothing and entertainment. Study 2 extended these findings by demonstrating that subjects exposed to death became more greedy and consumed more resources in a forest-management game. Results are discussed with regard to humanistic and terror-management theories of materialism.

Prosocial values and group assortation : Within an N-person prisoner's dilemma game.

Ninety-five freshmen each recruited three peers to play a "group bidding game," an N-person prisoner's dilemma in which anyone could win movie tickets depending on their scores in the game. Prior to playing, all participants completed a measure of prosocial value orientation. Replicating and extending earlier findings (Sheldon and McGregor 2000), our results show that prosocial participants were at a disadvantage within groups. Despite this vulnerability, prosocial participants did no worse overall than asocial participants because a counteracting group-level advantage arose for prosocials, who tended to be concentrated in groups. Implications of this assortative process for the egoism/altruism debate, and for hierarchical selection theory, are discussed.

Goal striving, need satisfaction, and longitudinal well-being: the self-concordance model.

An integrative model of the conative process, which has important ramifications for psychological need satisfaction and hence for individuals' well-being, is presented. The self-concordance of goals (i.e., their consistency with the person's developing interests and core values) plays a dual role in the model. First, those pursuing self-concordant goals put more sustained effort into achieving those goals and thus are more likely to attain them. Second, those who attain self-concordant goals reap greater well-being benefits from their attainment. Attainment-to-well-being effects are mediated by need satisfaction, i.e., daily activity-based experiences of autonomy, competence, and relatedness that accumulate during the period of striving. The model is shown to provide a satisfactory fit to 3 longitudinal data sets and to be independent of the effects of self-efficacy, implementation intentions, avoidance framing, and life skills.

Avoidance personal goals and the personality-illness relationship.

Three studies demonstrated that avoidance personal goals are positively related to physical symptom reports. These results were obtained (a) using both longitudinal and retrospective methodologies and (b) controlling for neuroticism and other alternative predictor variables. In 2 of the studies, a process model was validated in which perceived competence and perceived controlledness were shown to mediate the observed relationship between avoidance goals and symptomatology. Specifically, avoidance goals predicted perceived competence and perceived controlledness, and these variables in turn predicted longitudinal and retrospective symptom reports. Ancillary results help clarify the unique roles of neuroticism and avoidance goals as predictors of physical symptomatology.

Avoidance achievement motivation: a personal goals analysis.

The present research investigated one antecedent and various consequences of pursuing avoidance personal achievement goals over the course of a semester. The authors assessed participants' achievement-relevant goals using the newly devised Achievement Goals Questionnaire. The motive to avoid failure, assessed with self-report and projective measures, was established as an antecedent of avoidance goal pursuit. Avoidance regulation was shown to have deleterious consequences for a host of achievement-relevant and general well-being outcomes at the end of the semester, including longitudinal change in subjective well-being. Perceived competence was validated as a mediator of the direct relationships observed. The results highlight the need to attend to avoidance, as well as approach, forms of self-regulation and the need to consider both motive disposition and goal constructs in accounting for competence-relevant behavior.

Differences between accumulation of 99mTc-MIBI and 201Tl-thallous chloride in tumour cells: role of P-glycoprotein.

Both 99mTc-MIBI and 201Tl have been used for tumour imaging. It has recently been reported that 99mTc-MIBI is a substrate for P-glycoprotein (Pgp), a membrane pump which mediates multidrug resistance. We have evaluated the role of Pgp in the cellular accumulation of 201Tl by using sensitive and resistant strains of Chinese hamster ovary (CHO) fibroblasts (AuxB1 and CHRC5, respectively) grown in suspension culture. 201Tl accumulation was the same in sensitive and resistant cells, whereas 99mTc-MIBI accumulation was much lower in resistant cells than in sensitive ones. Down-modulation of Pgp with 100 microM verapamil did not alter cellular accumulation of 201Tl while it significantly increased 99mTc-MIBI accumulation in both types of cell. Similarly, 10 microM verapamil did not affect the rate of washout of 201Tl from preloaded cells, while 99mTc-MIBI washout was greatly reduced in the presence of verapamil. These results suggest that 201Tl will accumulate in both sensitive and resistant tumour cells, whereas 99mTc-MIBI will be extruded from resistant cells and therefore may be less useful for tumour detection when the tumour cells express high Pgp levels.

Labelling small quantities of monoclonal antibodies and their F(ab')2 fragments with technetium-99m.

Addition of sulfhydryl groups with 2-iminothiolane (2-IT) is an important new method for labelling monoclonal antibodies (mAb) and fragments with 99mTc. F(ab')2 fragments were prepared by digestion of 1B7.11 and BCD-F9 with pepsin. Optimal conditions for labelling 20-100 micrograms mAb or F(ab')2 involved a 2000:1 molar ratio of 2-IT:protein in phosphate buffer pH 7.4 for 30 min followed by addition of 99mTc-pertechnetate and stannous glucoheptonate. Recovered yields were > 70% and radiochemical purities were > 90% with a total preparation time of < 90 min.

Coherence and congruence: two aspects of personality integration.

Coherence and congruence-based measures of personality integration were related to a variety of healthy personality characteristics. Functional coherence was defined as occurring when participants' "personal strivings" (R.A. Emmons, 1986) help bring about each other or help bring about higher level goals. Organismic congruence was defined as occurring when participants strive for self-determined reasons or when strivings help bring about intrinsic rather than extrinsic higher level goals. Study 1 found the integration measures were related to each other and to inventory measures of health and well-being. Study 2 showed that these goal integration measures were also related to role system integration and were prospective predictors of daily mood, vitality, and engagement in meaningful as opposed to distracting activities.

A new technique for detecting fluorescently labelled cells at very low densities.

We have developed a new cytometric method that has the potential for detecting fluorescently labelled cells at very low densities against a high density background of non-fluorescing cells of similar size. The method uses a Waveform Analysis Interface which is an electronic device that is essentially an "add-on" to a flow cytometer. It takes the amplified fluorescence and scatter signals from the flow cytometer and measures their intensities at microsecond intervals. It can be programmed to react only to cells with specific characteristics and ignore all others. In this mode it is possible to detect fluorescently labelled cells at densities down to about 1.mL-1 against a background density of non-fluorescent cells of similar size of more than 1 x 10(7).mL-1. This application may have considerable potential for cancer diagnosis and therapy.