ABSTRACT
Common aspects have been revealed of structural and functional disorders of the biliary tract and intestine in elderly patients with digestive pathology. We recommend that lipotropic drugs, choleretics, cholekinetics, antioxidants and eubiotics be used in the treatment of the above patients.
Subject(s)
Biliary Tract Diseases/complications , Intestinal Diseases/complications , Aged , Antioxidants/therapeutic use , Biliary Tract Diseases/diagnosis , Biliary Tract Diseases/drug therapy , Cholagogues and Choleretics/therapeutic use , Female , Humans , Intestinal Diseases/diagnosis , Intestinal Diseases/drug therapy , Lipotropic Agents/therapeutic use , Male , Middle AgedABSTRACT
Using cluster analysis of analytic strips optical densities the lithogenic bile heterogeneity has been confirmed and different types, possessing a distinction totality of spectral and biochemical figures has been revealed. This study demonstrated tendency in process of formation of gallstone in cholelithiasis.
Subject(s)
Bile/metabolism , Cholelithiasis/metabolism , Spectrophotometry, Infrared , Cholecystitis/metabolism , Cholecystitis/surgery , Cluster Analysis , HumansABSTRACT
The ionization and conjugation effect on infrared spectra of bile acids has been studied. The interpretation of spectra of native bile absorption in the infrared range was conducted with allowance for different types of functional groups oscillations.
Subject(s)
Bile Acids and Salts/chemistry , Bile/chemistry , Cholesterol/chemistry , Cholic Acid , Cholic Acids/chemistry , Glycocholic Acid/chemistry , Humans , Phosphatidylcholines/chemistry , Serum Albumin/chemistry , Spectrophotometry, Infrared , Taurocholic Acid/chemistryABSTRACT
Our studies on phosphatide, a food concentrate, produced as a by-product during the extraction of an edible oil in the oil-extraction plants, showed its high efficacy in patients (n = 52) with abnormalities of the hepatobiliary system. The drug having more than 40 weight percent of phosphorus-containing lipids appeared to be efficacious not only in respect of the subjective status of the patients but also the functional state of the liver and paraments characterizing lipid metabolism.
Subject(s)
Biliary Tract Diseases/drug therapy , Food Additives/therapeutic use , Liver Diseases/drug therapy , Phospholipids/therapeutic use , Adult , Biliary Tract Diseases/physiopathology , Chronic Disease , Drug Evaluation , Female , Humans , Liver/drug effects , Liver/physiopathology , Liver Diseases/physiopathology , Liver Function Tests , Male , Middle AgedABSTRACT
Acute, subacute, and chronic experiments were performed to examine the toxicity, specific action, analgetic, and physicochemical properties of suicrepan derived from the porcine duodenal mucosa and the hormone secretin contained in it. Suicrepan was found to be an effective pancreatic extrasecretory function stimulant, by showing therapeutical benefits in experimental pancreatitis and analgesic effects. The drug was demonstrated to display a low toxicity.
Subject(s)
Secretin/pharmacology , Acute Disease , Analgesics/pharmacology , Animals , Chemical Phenomena , Chemistry, Physical , Dogs , Dose-Response Relationship, Drug , Drug Evaluation, Preclinical , Male , Mice , Pancreatic Juice/drug effects , Pancreatic Juice/metabolism , Pancreatitis/drug therapy , Rabbits , Rats , Secretin/chemistry , Secretin/therapeutic use , Secretin/toxicity , Time FactorsABSTRACT
Results are of a comparative analysis of immunological and biochemical parameters in 116 patients with duodenal ulcer before operative treatment and in the follow-up (1-3 years) after different types of vagotomy. A close relationship has been established between the immune and neurohumoral links of regulation and state of the acid forming gastric function in patients with ulcer disease.
