1.
Bioorg Khim
; 34(4): 540-5, 2008.
Article
in Russian
| MEDLINE
| ID: mdl-18695728
ABSTRACT
New lupane beta-enaminoketones were synthesized by interaction of methyl 2-hydroxymethylene-3-oxolup-20(29)-en-28-oate with aliphatic amines. Immunotropic activity was found for some of these compounds.
Subject(s)
Immunosuppressive Agents/chemical synthesis , Triterpenes/chemical synthesis , Animals , Antibody Formation , Esters , Immunity, Cellular , Immunosuppressive Agents/chemistry , Immunosuppressive Agents/immunology , Ketones/chemical synthesis , Ketones/immunology , Magnetic Resonance Spectroscopy , Male , Mice , Spectrophotometry, Infrared , Structure-Activity Relationship , Triterpenes/chemistry , Triterpenes/immunology
2.
Bioorg Khim
; 34(1): 136-40, 2008.
Article
in Russian
| MEDLINE
| ID: mdl-18365749
ABSTRACT
2-Alkylaminomethylene-19beta,28-epoxyolean-3-ones were obtained by interaction of 2-hydroxymethylene-19beta,28-epoxyolean-3-one with aliphatic amines. Some of the resulting substances exhibit immunotropic activity.
