Subject(s)
Dental Pulp/physiology , Pain/physiopathology , Receptors, Adrenergic/physiology , Receptors, Cholinergic/physiology , Synapses/physiology , Animals , Arecoline/pharmacology , Atropine/pharmacology , Dihydroergotoxine/pharmacology , Electric Stimulation , Evoked Potentials/drug effects , Isoproterenol/pharmacology , Lobeline/pharmacology , Norepinephrine/pharmacology , Parasympatholytics/pharmacology , Phentolamine/pharmacology , Propranolol/pharmacology , RabbitsABSTRACT
Topic organization of the dental representation was studied in experiments on rabbits by the method of induced potentials. Every tooth proved to be locally represented in the sensory-motor zone of the brain cortex. These zones do not overlap in the case of stimulation of the threshold strength. Topic dental projection region occupies a territory including fields Par I, Praecag, Preacgr, and PC.
Subject(s)
Motor Cortex/physiology , Somatosensory Cortex/physiology , Tooth/innervation , Animals , Brain Mapping , Electric Stimulation , Electrophysiology , Neurons, Afferent/physiology , Pain , Rabbits , Reaction Time/physiology , Toothache/physiopathologyABSTRACT
A method of obtaining antineuronal and antiglial immune sera is described. Data of the quantitative immunochemical analysis of the antigens of the neuronal and glial fractions of the rat brain are presented. The neurons proved to contain 4, and the glia--3 brain-specific proteins; one or two of them are common for these cell fractions.
Subject(s)
Antigens , Brain/cytology , Neuroglia/immunology , Neurons/immunology , Animals , Brain/immunology , Immunodiffusion , RatsABSTRACT
The activity of acetylcholinesterase and butyrilcholinesterase was studied during prolonged seizures developing from a primary-cortical focus. The activity was found to spread both along the wide limbic system, which indicates to participation of cholinergic agents in processes of "recurrent generalization" of excitations, and along the horizontal system of fibers connecting both hemispheres. This latter finding indicates to participation of cholinergic mediatory mechanisms in formation of seizures.
Subject(s)
Acetylcholinesterase/metabolism , Brain/enzymology , Butyrylcholinesterase/metabolism , Cholinesterases/metabolism , Seizures/enzymology , Animals , Globus Pallidus/enzymology , Histocytochemistry , Limbic System/enzymology , Mesencephalon/enzymology , Neural Pathways , Rabbits , Reticular Formation/enzymology , Thalamic Nuclei/enzymologyABSTRACT
The authors studied the significance in the "maturation" of the cortical chronic experimental epileptogenic focus. The studies were conducted in rabbits with the use of registration methods of a summarized bioelectric activity and activation of subcortical formation by electric current. It was established that the activation of inhibitory structures in the preconvulsive period facilitated the inhibition of "maturation" of the initial-cortical epileptogenic focus and an easier development of the convulsive attack in comparison with the control group (without stimulation of subcortical nuclei), while the activation of generalizing formations lead to more severe convulsive attacks.
Subject(s)
Caudate Nucleus/physiopathology , Cerebral Cortex/physiopathology , Hypothalamus/physiopathology , Seizures/physiopathology , Animals , Brain Mapping , Electric Stimulation , Electrophysiology , Neural Pathways , RabbitsABSTRACT
Intraventriculare injections have brough evidence that alpha-adrenomimetic norepinephrine and beta-adrenomimetic isopropylnorepinephrine augment in the senso-motor region of the cortex the amplitude of primary responses evoked through a dental pulp stimulation. The alpha-adrenoblocking agents--dihydroergotoxin and phentolamine and the beta-edrenoblocking agent propranolol force down the amplitude of primary responses. The sphere of the drugs action is presumed to be the thalamic nuclei.