ABSTRACT
In the title compound, C22H22ClN3O4S, which has potential non-steroidal anti-inflammatory activity, the benzo-thia-zine and cyclo-hexenone rings both adopt a distorted sofa conformation while the 4H-pyrane ring adopts a very flattened sofa conformation. The two bicyclic fragments are skewed to each other, with the dihedral angle between their least-squares planes being 72.8â (1)°. In the crystal, the mol-ecules form a hydrogen-bonded chain parallel to the a axis due to N-Hâ¯O and N-Hâ¯Cl hydrogen bonds. Neighbouring chains are linked by C-Hâ¯N, C-Hâ¯O and π-π stacking inter-actions. Hirshfeld surface analysis was used to investigate the importance of the different types of inter-molecular inter-actions whose contributions are: Hâ¯H = 44.7%, Oâ¯H/Hâ¯O = 21.8%, Nâ¯H/Hâ¯N = 11.9%, Câ¯H/Hâ¯C = 9.5%, Clâ¯H/Hâ¯Cl = 7.2%. Parts of the mol-ecule, viz. the phenyl ring and the ethyl side chain, are equally disordered over two sets of sites.