[Principles of safe endoscopic surgery on the endocrine organs of the neck]. / Printsipy bezopasnykh endoskopicheskikh operatsii na endokrinnykh organakh shei.

OBJECTIVE: To emphasize the main stages of safe endoscopic surgery on endocrine organs of the neck. MATERIAL AND METHODS: There were 79 patients with diseases of thyroid and parathyroid glands who underwent surgery between 2018 and 2021. Of these, 69 ones underwent transaxillary thyroidectomy, 10 patients underwent transaxillary parathyroidectomy. RESULTS: At initial stage of development of this technique, we obtained 2 intraoperative and 2 postoperative complications. Adverse events were completely cured. CONCLUSION: Endoscopic procedures on the endocrine organs of the neck are a safe alternative to traditional approaches. There are certain advantages of this approach. Compliance with surgical technique and focusing on dangerous stages minimize the risk of complications.

[Management of mucinous tumor of appendix]. / Lechenie patsientki s mutsinoznoi opukhol'yu cherveobraznogo otrostka.

Low-grade mucinous tumors (MT) of the appendix are rare malignancies. One of the most formidable complications of these tumors is mucin depositing in the peritoneum with development of peritoneal pseudomyxoma. Currently, there are no single clinical - pathomorphological classification and treatment approach to these tumors. This situation is complicated by the fact that tumor of the appendix cannot be preoperatively suspected in many cases and MT is detected after appendectomy for acute appendicitis or its complications. Thus, prognosis of patients is deteriorated.

[INFLUENCE OF TITANIUM COATING ON THE BIOCOMPATIBILITY OF POLYPROPYLENE IMPLANTS].

Comparative analysis of the proliferative activity of inflammatory cells and distribution of collagen types I and III was carried out around the net materials of polypropylene and titanium coating polypropylene using im- munohistochemical method and polarization microscopy. Experimental modeling of implanted mesh material were made in the soft tissues of the lumbar region of rats. On the 7th postoperative day, quantitative analysis of proliferating cells delected using antibodies to the Ki-67 protein showed, a significant decrease (p < 0.001) in the number of proliferating cells around the network elements of the polypropylene (29.1 ± 5.7 %), when com- pared to similar figures of infiltrates in titanium coating polypropylene (33.6 ± 3.1 %). Similar patterns were found on the 30th day of the experiment--15.9 ± 4.3 and 26.9 ± 3.6%--respectively (p < 0.001). Different types of collagen fibers in the granulomas around various types of implanted mesh material were detected on sections stained with Sirius red at polarizing light. On the 7th day after surgery, the ratio of collagen fibers ty- pe I and III in granulomas around the mesh material made of polypropylene was 1.085 ± 0.022 and this rati around materials of titanium coated polypropylene was higher--1.107 ± 0.013 (p = 0.017). On the 30th posto- perative day in the interface area ratio I/III collagen significantly increased and amounted to 1.174 ± 0.036 and 1.246 ± 0.102, respectively (p = 0.045). Assessing the impact of the use of titanium as a coating on the po- lypropylene, it can be argued that it promotes the formation of collagen I type and a more mature connective tis- sue around the mesh of the implants.