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1.
Zhongguo Zhong Yao Za Zhi ; 44(24): 5488-5495, 2019 Dec.
Article in Chinese | MEDLINE | ID: mdl-32237399

ABSTRACT

Cosmetics containing botanic ingredients have been used from thousands of years up to now in China. Because of the consumers' demand for health and beauty,the number of products about " botanic" have been growing rapidly in the cosmetics market,which has played an important role in upgrading the industry and enhancing the international competitiveness nowadays. Therefore,to strengthen the management about used botanic raw materials in cosmetics products and revise the application regulation of new raw materials has become an important work to ensure product quality,promote the healthy and stable development of cosmetic business. The article summarizes the related mandatory regulations and standards about botanic ingredients which used as activity function in major cosmetic business countries or regions. Furthermore,the information of botanic ingredients commonly used in non-special cosmetics notification and special cosmetic registration system were described to expect the better application and development.


Subject(s)
Consumer Product Safety , Cosmetics/standards , Plant Preparations/standards , China , Cosmetics/legislation & jurisprudence , Government Regulation
2.
Zhongguo Zhong Yao Za Zhi ; 42(2): 307-310, 2017 Jan.
Article in Chinese | MEDLINE | ID: mdl-28948736

ABSTRACT

To study the alkaloids from Melodinus moraei,seven compounds were separated and purified by column chromatography over silica gel, reverse phase silica gel and preparative HPLC. Their chemical structures were elucidated by MS and spectral data (1H-NMR, 13C-NMR) as scandine(1),tabersonine(2),melodinine N(3),melodinine P(4), melodinine T(5),19-epimeloscandonine(6),16-hydroxy-19S-vindolinine(7). Compounds 1-7 were isolated from M. moraei for the first time.The bioassays showed all tested samples displayed antitumor activity against the cell lines such as A549,PC-3,HGC-27 and HL-60.


Subject(s)
Alkaloids/chemistry , Apocynaceae/chemistry , Drugs, Chinese Herbal/chemistry , Cell Line, Tumor , Humans , Molecular Structure , Phytochemicals/chemistry , Proton Magnetic Resonance Spectroscopy
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