1.
Zhonghua Yi Xue Yi Chuan Xue Za Zhi
; 29(5): 570-2, 2012 Oct.
Article
in Chinese
| MEDLINE
| ID: mdl-23042396
ABSTRACT
OBJECTIVE: A R1210C mutation of complement factor H (CFH) gene has been associated with age-related macular degeneration (AMD) in Caucasian population. This study was to verify above association in Han Chinese population. METHODS: The mutation was detected by direct sequencing in 258 patients with wet AMD and 426 matched controls. RESULTS: The R1210C mutation has not been identified in either sample. CONCLUSION: The R1210C mutation in CFH gene is not associated with AMD in Han Chinese population.