1.
J Org Chem
; 81(1): 309-17, 2016 Jan 04.
Article
in English
| MEDLINE
| ID: mdl-26641939
ABSTRACT
A fast catalytic synthesis of multisubstituted quinazolines from readily available amidines via visible light-mediated oxidative C(sp(3))-C(sp(2)) bond formation has been established. This reaction is a metal-free oxidative coupling catalyzed by a photoredox organocatalyst. The protocol features low catalyst loading (1 mol %).