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1.
ANZ J Surg ; 92(9): 2123-2128, 2022 09.
Article in English | MEDLINE | ID: mdl-35490335

ABSTRACT

BACKGROUND: The One Anastomosis Gastric Bypass (OAGB) is a relatively novel procedure. Studies have demonstrated that it is at least as effective as other bariatric procedures but with fewer major complications and shorter operating time, yet OAGB is performed less partially due to a paucity of supportive evidence. We report the outcomes of a prospectively maintained database of patients undergoing laparoscopic OAGB. METHODS: All OAGB procedures performed by two surgeons across two hospitals from 2016 to 2019 were recorded in a prospectively maintained database. Patients with at least 1 year of follow up were included in this study and missing data was obtained from patient records. The primary outcome was percentage excess weight loss (EWL). The secondary outcome was surgical complication rate. RESULTS: Three hundred and twenty-five patients with a mean pre-operative body mass index of 43.3 kg/m2 were included. The majority (85.2%) had a biliopancreatic limb length of 150 cm. The median EWL was 74.2% and 79.4% of patients achieved at least 50% EWL. There were no deaths, the overall re-operation rate was 4.9% and 1.9% of patients developed stomal ulcers. Seven patients went on to have a Roux-en-Y conversion predominantly for symptomatic reflux. CONCLUSION: OAGB leads to excellent weight loss and is at least as safe as more commonly performed procedures, it may be a suitable treatment for a greater number of patients than it is being offered to at present.


Subject(s)
Gastric Bypass , Obesity, Morbid , Anastomosis, Roux-en-Y , Australia/epidemiology , Gastric Bypass/adverse effects , Gastric Bypass/methods , Humans , Obesity, Morbid/surgery , Retrospective Studies , Weight Loss
2.
Ann Med Surg (Lond) ; 53: 16-19, 2020 May.
Article in English | MEDLINE | ID: mdl-32280460

ABSTRACT

INTRODUCTION: Diaphragmatic injury is a rare clinical entity which presents a diagnostic and therapeutic challenge. It is three times more common following blunt trauma than penetrating trauma and results in larger tears. A high index of suspicion is required to diagnose diaphragmatic injury. A missed diagnosis following acute injury can later result in life-threatening complications. CASE PRESENTATION: We describe the successful management of a right hemidiaphragmatic injury presenting two weeks following blunt thoracoabdominal trauma using a laparoscopic mesh repair. DISCUSSION: Diaphragmatic injury is rare, with right-sided injuries less common due to the buffering effect of the liver. The diagnosis is made within 24 hours of injury in 75% of cases (Haranal and et al., 2018) [1]. In our patient, symptoms of a right-sided diaphragmatic injury manifested two weeks following a motor vehicle collision. A CT scan of the chest and abdomen confirmed the diagnosis. According to DeBlasio, intermittent symptoms of visceral herniation or incorrect x-ray interpretation are the main reasons for a delayed diagnosis (DeBlasio et al., 1994) [2]. Contrary to common practice where thoracotomy is the preferred method for repair in the absence of associated abdominal injuries, we demonstrated that a right-sided diaphragmatic injury can be successfully managed with a laparoscopic mesh repair. CONCLUSION: Traumatic diaphragmatic injury remains a challenge to emergency physicians and trauma surgeons. Clinicians should be aware of the differing clinical presentations, investigations, and management. Surgical repair can be achieved via laparoscopy, thoracoscopy, laparotomy, and/or thoracotomy. In the case of an isolated right-sided diaphragmatic injury, laparoscopic mesh repair should be considered.

5.
Transplantation ; 87(8): 1112-4, 2009 Apr 27.
Article in English | MEDLINE | ID: mdl-19384154

ABSTRACT

Long-term survival post lung transplant is reduced significantly by Bronchiolitis Obliterans Syndrome. It is suggested that extra-esophageal reflux disease is a risk factor for Bronchiolitis Obliterans Syndrome and that antireflux surgery may be beneficial. However, practice between centers varies greatly. We suggest a need for improved evidence and standardization.


Subject(s)
Bronchiolitis Obliterans/etiology , Gastroesophageal Reflux/epidemiology , Gastroesophageal Reflux/surgery , Lung Transplantation/adverse effects , Bronchiolitis Obliterans/mortality , Bronchiolitis Obliterans/surgery , Follow-Up Studies , Gastroesophageal Reflux/mortality , Humans , Lung Transplantation/mortality , Reproducibility of Results , Survival Rate , Survivors
8.
Eur J Gastroenterol Hepatol ; 18(10): 1043-5, 2006 Oct.
Article in English | MEDLINE | ID: mdl-16957508

ABSTRACT

Lichen planus of the oesophagus is rare with a predilection for middle-aged to elderly women. There is a potential risk of malignant transformation to squamous cell carcinoma. Squamous cell carcinoma of the oesophagus still accounts for 30-40% of oesophageal cancer cases in the west and is almost exclusively the disease still encountered in the rest of the world. An increased awareness of oesophageal lichen planus is suggested in patients with cutaneous, oral or vulval disease. Endoscopic investigation of patients with lichen planus, possibly initially limited to those with oesophageal symptoms, and consideration of surveillance in patients with proven oesophageal lichen planus, will aid understanding of natural history of lesions and may help detect early stage tumours. Squamous cell carcinoma still accounts for 30-40% of oesophageal cancer cases in the west and is almost exclusively the disease still encountered elsewhere. Lichen planus of the oesophagus is potentially a premalignant condition for squamous cell carcinoma that could be surveilled in order to detect early-stage tumours with a consequent greater chance of cure. Oesophageal lichen planus is, however, rare, frequently asymptomatic and although the majority of cases occur in conjunction with lichen planus in other sites, the oesophageal features may be subtle and easily missed by endoscopic assessment. Furthermore, the histological changes are difficult to interpret and there may be significant underreporting. As a consequence, the true prevalence of these lesions is hard to determine. The difficulties in detection may mean that we are underestimating the frequency of oesophageal lichen planus. Endoscopic detection may be aided by the use of magnification indigo carmine chromoendoscopy and this warrants further evaluation. The risk of malignant transformation is currently unknown but may parallel that of oral lesions at approximately 1-3%. An increased awareness of the condition can only help to identify more cases and increase our understanding of this interesting condition.


Subject(s)
Esophageal Diseases/diagnosis , Lichen Planus/diagnosis , Aged , Carcinoma, Squamous Cell/diagnosis , Disease Progression , Esophageal Neoplasms/diagnosis , Female , Humans , Middle Aged , Precancerous Conditions/diagnosis
9.
Expert Rev Pharmacoecon Outcomes Res ; 3(2): 179-88, 2003 Apr.
Article in English | MEDLINE | ID: mdl-19807365

ABSTRACT

For many years indicators such as mortality rates, levels of morbidity and cure measured the success of treatments for esophageal cancer. However, it is now recognised that quality of life (QOL) is an important measure of outcome. This is especially so for esophageal cancer, where the therapeutic options include curative treatments or palliative care. A number of measures have been developed but few QOL studies have been conducted in esophageal cancer. A health economics approach to outcome measurement, that seeks to quantify individual preferences (or utilities), offers a number of advantages. However, it is important to recognize that these methods are still under development. Nevertheless, by seeking to measure the strength of individual preferences, utilities provide additional information for decisions regarding which treatments provide the most optimal outcomes.

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