[Treatment of non accomodated concomitant strabismus].

The aim of the study was comparative evaluation of surgical treatment and complex pre and postoperative pleoptic, orthoptic, diploptic treatment of non accommodated concomitant strabismus and identification of the optimum age for surgical treatment of strabismus. The 75 patients (from 2 to 10 years old) with manifested concomitant convergent strabismus were divided into two groups: patients operated at the age from 2 to 4 years old; patients operated at the age of 4-10 years). The 75 of patients operated at the age from 2 to 4 years old, which underwent orthoptic-diploptic treatment pre- and postoperatively got binocular vision showed the full recovery in only 40% of cases of the same age-group undergone the surgical treatment in combination with the direct occlusion. Binocular vision was achieved in 68% of patients operated at the age of 4-10 years with complex treatment, and in 25% in patients of the same age group with surgical treatment plus occlusion. The findings showed the efficacy of complex treatment as well as pre and postoperative pleoptic-orthoptic-diploptic treatment of strabismus and direct occlusion. Thus, the results of this study suggest that the delay of surgical treatment limits the ability to obtain optimal results.

[Experimental investigation of general toxiology of antioxidant eyedrops davicol].

Authors examined the toxicity of antioxidant eye drops--davikoli. Antioxidants play important role in protecting the body from the formation of very dangerous substances referred to as free radicals. On the basis of honey an eye drops with high antioxidant activity--davicoli has been developed. The ocular effects of eye drops have been measured in a placebo-controlled double-blind study in 44 mice, 44 rats, 40 sea pigs and 20 chinchilla rabbits. Preclinical study revealed that eye drops davikoli are safe and non-toxic. During the investigation anti-inflammation features of eye drops davicoli was discovered.

[Assessment of the lower threshold in autoregulation of the blood supply of the optic nerve disk].

Existence of the autoregulation phenomenon in the blood supply system of the optic nerve has been established in the 1990; however, some of its quantitative and qualitative characteristics still require clarification. The goal of the present work was assessment of the lower margin in autoregulation of the blood supply of the optic nerve in the rabbit in conditions of attenuated level of perfusion pressure. Total of six adult rabbits weighing 2.5-3.0 kg, anesthetized with urethane (0.9-1.1 g/kg) were investigated in acute experiments. Intensity of the local blood flow in the optic nerve disk was evaluated quantitatively by means of the hydrogen clearance. The frontal chamber of an eye was punctured with syringe needle, which via silicon tube was attached to the reservoir filled with artificial aqueous humor. Adjustment of vertical position of the reservoir provided different levels of the intraocular pressure. Calculation of the perfusion pressure of the eye was made according to mean level of the systemic arterial pressure, intraocular pressure, and a constant, which depends on an animal species. The results obtained allow suggesting with a certain degree of precision that elevation of the intraocular pressure to about 40-50 mmHg does not alter the blood supply of the optic nerve disk. Its further increase however leads to almost linear dependence between elevation of the intraocular pressure and decrease of the blood supply of the optic nerve disk. Meanwhile, the systemic arterial pressure should be considered as well, because volume of the perfusion pressure in the eye is determined by difference between systemic arterial- and intraocular pressures.

[Comparative evaluation of morphometric and intravital measurements of the intraorbital portion of the optic nerve and of the distance from the posterior pole of the eyeball to the common tendinous ring]. / Sravnitel'naia otsenka morfometricheskikh i prizhiznennykh izmerenii intraorbital'noi chasti zritel'nogo nerva i rasstoianiia ot zadnego poliusa glaznogo iabloka do myshechnogo sukhozhil'nogo kol'tsa.

The paper describes results of comparative assessment of morphometric and in vivo measurements of the intraorbital part of the optic nerve and the distance from the posterior pole of the eye ball to the muscular tendon ring. It is shown that the method of ultrasound scanning is accurate enough and may be used for measuring the length of the intraorbital part of the optic nerve and the distance from the posterior pole of the eye ball to the muscular tendon ring in each concrete case.