A Tertiary Care Centre Experience of Recurrent Giant Cell Tumor Around the Knee Joint.

INTRODUCTION: Giant cell tumor (GCT) is a benign but locally aggressive bone tumor. It has a peak incidence between 30-40 years with a predilection for the epiphyseal/metaphyseal region of bone. The most common locations for bone GCT are the distal femur, proximal tibia, distal radius, and sacrum in decreasing order. MATERIAL AND METHODS: In this retrospective study, 22 patients (13 females and nine males) with recurrent giant cell tumors around the knee joint between 2009-2022, with a mean age of 30.2 years (range: 18-55) were included. The patients were followed up monthly for three months, three-monthly for the next two years, six-monthly for the next five years, and thereafter, yearly. The mean follow-up period was 36.97 months (range 23-120 months). RESULTS: There were 19 recurrences after curettages and three after resections. Re-extended curettage was done in 17 cases and the resultant cavities were filled with autologous bone grafts in six and with polymethyl methacrylate (PMMA) cement in the other 11 cases. Reconstruction with megaprosthesis was done in two patients whereas knee arthrodesis was done in two patients after wide resection. The average Musculoskeletal Tumor Society (MSTS) score of our series of 22 patients was 23.1 (Range: 19-30). CONCLUSION: Campanacci grade 1 and 2 lesions can be successfully treated with extended curettage and bone grafting/bone cementing. For patients with grade 3 lesions, there are two options available according to the financial status of the patient; the first option is reconstruction with prosthesis and the other option is arthrodesis.

Recurrent Giant Cell Tumour of Distal End Radius: Treatment and Outcomes After Further Surgeries.

INTRODUCTION: Distal end radius is the second most common location for giant cell tumours (GCTs) followed by the knee. Like at any other location, they are treated with extended curettage or resection but reportedly have an increased propensity for recurrence. This study aims to treat the recurrent distal end radius GCTs and their outcome after further surgeries. PATIENTS AND METHODS: This study was conducted retrospectively from 2009 to 2021 and included 32 patients with recurrent distal end radius GCTs with a mean age of 29.53 years (range: 18-45 years). Twenty-five recurrences occurred after curettage and seven after resection. Twelve lesions were treated with further extended curettage. Nineteen recurrent lesions were treated with resection and arthrodesis. One out of two soft tissue recurrences was treated with en bloc resection. The mean follow-up period was 45.25 months (range: 24-120). RESULTS: The patients with joint preservations treated with further curettage and those where resection of soft tissue recurrences was done with salvage of joint had better functional outcomes with a mean Musculoskeletal Tumor Society (MSTS) score of 26.53 (Range: 22-30). The cases with arthrodesis had an average score of 23.75 (Range: 20-26). The overall average MSTS score was 24.89. CONCLUSIONS: We conclude that local recurrence contained within the bone can be re-curetted. The isolated soft tissue recurrences can be re-excised. The bony lesions with extensive soft tissue extension should be treated with resection and reconstruction. The re-recurrence rate after further adequate treatment does not increase much.

Outcomes of Wide Resection of Soft-Tissue Sarcoma of the Extremity: A Retrospective Analysis.

Background Soft-tissue sarcomas (STSs) are a rare heterogeneous group of tumors. Good functional results can be achieved with tumor excision in combination with suitable supplemental adjuvant therapies if needed. This study aimed to investigate the outcomes of wide resection of STS of the extremities. Methodology In this retrospective study, a total of 139 patients diagnosed with STS of the extremities by radiological and/or histopathological study/biopsy were included. All patients irrespective of metastasis were included. Results The mean age of the patients in our study was 43.5 ± 18.89 years. Overall, the mean tumor size was found to be 11.81 ± 6.218 cm. Malignant fibrous histiocytoma was the most common histology encountered (41%). Synovial sarcoma was the second most common histology encountered (14.38%). Recurrence was observed in 14 (10.1%) patients. The overall survival was 64.7% in our study. Conclusions The surgical margin achieved during the surgery is the most detrimental factor in local tumor control, and the overall survival of the patient after resection mainly depends on the stage of the tumor.

A Rare Case Report on Neurilemmoma of the Superficial Peroneal Nerve and a Review of the Literature.

Neurilemmoma is a form of nerve tumor that develops from the nerve sheaths. It is a slow-growing tumor with a rare malignant transformation. It has an incidence rate of less than 1% in lower limbs and its origin in the superficial peroneal nerve is an extremely rare occurrence. In this report, we present a case of neurilemmoma of the superficial peroneal nerve in a 67-year-old male who presented with complaints of pain and swelling at the lateral aspect of the leg. The swelling was enucleated while preserving the main nerve trunk. The patient was found to be asymptomatic after a two-year postoperative period.

Comparative study of medial opening wedge high tibial osteotomy using fixator-cum-distractor device or locking plate in medial unicompartmental osteoarthritis of knee.

OBJECTIVE: The aim of our study was to evaluate the role of medial opening wedge high tibial osteotomy (MOWHTO) in medial unicompartmental osteoarthritis of the knee and compare two different fixation devices for stability, duration, outcome, and complications. METHODS: Fifty-seven patients (60 knees) of age < 60 yrs and either sex with medial unicompartmental osteoarthritis of the knee were divided into 2 groups. Twenty-four patients (25 knees) in Group I underwent MOWHTO using fixator-cum-distractor and 33 patients (35 knees) in Group II underwent MOWHTO using locking plate osteosynthesis. The results were assessed by VAS, KOOS and WOMAC score. RESULTS: Mean age of the patients in Group I was 53.13 ±â€¯5.20 years and 51.32 ±â€¯6.91 years in Group II. Mean preoperative varus deviation was 11.97 ±â€¯3.34° in Group I and 11.78 ±â€¯3.05° in Group II which was corrected to 3.27 ±â€¯1.75° and 3.56 ±â€¯1.47° valgus respectively. All the patients achieved full weight bearing by 35th day postoperatively in Group I with the mean of 30.27 ±â€¯2.71 days and 38th day in Group II with the mean of 30.32 ±â€¯3.08. The VAS, KOOS, and WOMAC score improved significantly postoperatively in both the groups. CONCLUSION: The difference between the two methods of fixation was statistically insignificant. Fixator-cum-distractor is minimally invasive giving good control over the final limb alignment; however, it is cumbersome with less patient compliance and has complications like pin tract infection. Locking plate provides better fixation stability than fixator-cum-distractor even without bone grafting; however, it is an invasive procedure requiring more soft tissue exposure and precise amount of wedge removal.