ABSTRACT
The results from examination of intestinal microflora and immune status in 75 patients with nonspecific ulcerative colitis with different degree of disease seriousness are presented. The deviations in the composition of normal microflora were primarily expressed in a decrease of the number of bifidobacteria. In 64.9% of patients the disease proceeded against the background of deficit of T-cellular immunity link. The sufficiently expressed bacteriological and immunological efficiency of complex therapy including preparation from spore-forming bacteria as a normalizer of microflora is shown.
Subject(s)
Bacillus , Biological Factors/therapeutic use , Colitis, Ulcerative/drug therapy , Anti-Bacterial Agents/therapeutic use , Biological Products/therapeutic use , Colitis, Ulcerative/immunology , Colitis, Ulcerative/microbiology , Drug Evaluation , Feces/microbiology , Female , Humans , Immunity, Cellular/drug effects , Intestine, Large/microbiology , Male , Spores, BacterialABSTRACT
Enterodes and splenin were used in the treatment of patients with ulcerative colitis (idiopathic proctocolitis) in association with routine drug treatment while steroids were not employed. Results indicate increase of the therapeutic effect due to improvement of regeneration of the intestine and improvement of the immunity status.
