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Acta Chim Slov ; 67(2): 638-643, 2020 Jun.
Article in English | MEDLINE | ID: mdl-33855579

ABSTRACT

The hydrazone compound N'-(2-hydroxybenzylidene)-3-methylbenzohydrazide (H2L) was prepared. With H2L and copper acetate a new copper complex [Cu(HL)(NCS)]·CH3OH was synthesized. Both the hydrazone and the copper complex were characterized by physico-chemical methods and single crystal X-ray diffraction techniques. The complex is a thiocyanato-coordinated copper(II) species. The Cu atom in the complex is in square planar geometry. The complex is a promising urease inhibitor.


Subject(s)
Coordination Complexes/chemistry , Enzyme Inhibitors/chemistry , Hydrazines/chemistry , Urease/antagonists & inhibitors , Coordination Complexes/chemical synthesis , Copper/chemistry , Enzyme Assays , Enzyme Inhibitors/chemical synthesis , Hydrazines/chemical synthesis , Molecular Structure , Urease/chemistry
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