ABSTRACT
AIM: To evaluate the safety of therapeutic bandage contact lens for post-cataract surgery patients and to illustrate its efficacy on post-operative comfort and tear-film stability. METHODS: A total of 40 participants were recruited and randomly divided into two groups. Group one was instructed to wear bandage contact lenses for a week and use antibiotic eye drops for a month since the first day after surgery. Group two received sub-conjunctival injection of tobramycin and was asked to wear eye pads on the first day after surgery and then were instructed to use antibiotic eye drops as the first group did. Ocular surface disease index (OSDI) questionnaire, slit-lamp microscope examination of tear break-up time (TBUT), corneal fluorescein score (CFS), tear meniscus height (TMH) together with anterior segment optical coherence tomography (AS-OCT) and corneal topography were evaluated preoperatively and postoperatively. RESULTS: The subjective feeling (P=0.004), TBUT (P<0.001) and TMH (P=0.02) post-surgery had improved in patients who used bandage contact lenses compared with those who did not at 1wk post-surgery. Until three month postoperatively, the comfort degree (P=0.004) and TMH (P=0.01) of group two were still worse than group one. Moreover, TBUT (P<0.001) and CFS (P=0.004) of the group with eye pads got worse than the results before, whereas the group with bandage contact lenses recovered to normal. None of these patients had infections or other complications. CONCLUSION: Wearing therapeutic bandage contact lens after cataract surgery, compared with traditional eye-pads, is a safe method to improve tear-film stability and reduce post-operative discomfort without hindering corneal incision recovery.
ABSTRACT
AIM: To detect the relationship between infusion pressure and postoperative ganglion cells function. METHODS: This prospective observational cohort study included sixty-one eyes that underwent uncomplicated cataract surgery. Patients were divided into two groups according to infusion time (IT) recorded using surgery equipment [Group A: IT>ITmean (27 eyes); Group B: IT
ABSTRACT
Aging includes various changes, from the dysfunction of different organs to cellular damages. Recent years, there is a growing attention on the relationship between aging and endothelial cell damage. Aging bodies' endothelial cells are damaged through many ways, all contribute to structural and functional changes. And these pathways are being researched more and more deeply. This paper reviews the change of aging organism and the effects on endothelial cells, focuses on the different pathways on endothelial damage, and also discusses the relevant regulatory factors, which can be treated as new direction for inhibiting endothelial damages and provide relevant strategies for delaying damages.
