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1.
IEEE Trans Med Imaging ; 42(11): 3269-3282, 2023 11.
Article in English | MEDLINE | ID: mdl-37227904

ABSTRACT

Semi-supervised learning via teacher-student network can train a model effectively on a few labeled samples. It enables a student model to distill knowledge from the teacher's predictions of extra unlabeled data. However, such knowledge flow is typically unidirectional, having the accuracy vulnerable to the quality of teacher model. In this paper, we seek to robust 3D reconstruction of stereo endoscopic images by proposing a novel fashion of bidirectional learning between two learners, each of which can play both roles of teacher and student concurrently. Specifically, we introduce two self-supervisions, i.e., Adaptive Cross Supervision (ACS) and Adaptive Parallel Supervision (APS), to learn a dual-branch convolutional neural network. The two branches predict two different disparity probability distributions for the same position, and output their expectations as disparity values. The learned knowledge flows across branches along two directions: a cross direction (disparity guides distribution in ACS) and a parallel direction (disparity guides disparity in APS). Moreover, each branch also learns confidences to dynamically refine its provided supervisions. In ACS, the predicted disparity is softened into a unimodal distribution, and the lower the confidence, the smoother the distribution. In APS, the incorrect predictions are suppressed by lowering the weights of those with low confidence. With the adaptive bidirectional learning, the two branches enjoy well-tuned mutual supervisions, and eventually converge on a consistent and more accurate disparity estimation. The experimental results on four public datasets demonstrate our superior accuracy over other state-of-the-arts with a relative decrease of averaged disparity error by at least 9.76%.


Subject(s)
Endoscopy , Imaging, Three-Dimensional , Humans , Neural Networks, Computer , Probability , Supervised Machine Learning
2.
IEEE Trans Med Imaging ; 41(10): 2788-2802, 2022 10.
Article in English | MEDLINE | ID: mdl-35482699

ABSTRACT

Registration of brain MRI images requires to solve a deformation field, which is extremely difficult in aligning intricate brain tissues, e.g., subcortical nuclei, etc. Existing efforts resort to decomposing the target deformation field into intermediate sub-fields with either tiny motions, i.e., progressive registration stage by stage, or lower resolutions, i.e., coarse-to-fine estimation of the full-size deformation field. In this paper, we argue that those efforts are not mutually exclusive, and propose a unified framework for robust brain MRI registration in both progressive and coarse-to-fine manners simultaneously. Specifically, building on a dual-encoder U-Net, the fixed-moving MRI pair is encoded and decoded into multi-scale sub-fields from coarse to fine. Each decoding block contains two proposed novel modules: i) in Deformation Field Integration (DFI), a single integrated deformation sub-field is calculated, warping by which is equivalent to warping progressively by sub-fields from all previous decoding blocks, and ii) in Non-rigid Feature Fusion (NFF), features of the fixed-moving pair are aligned by DFI-integrated deformation field, and then fused to predict a finer sub-field. Leveraging both DFI and NFF, the target deformation field is factorized into multi-scale sub-fields, where the coarser fields alleviate the estimate of a finer one and the finer field learns to make up those misalignments insolvable by previous coarser ones. The extensive and comprehensive experimental results on both private and two public datasets demonstrate a superior registration performance of brain MRI images over progressive registration only and coarse-to-fine estimation only, with an increase by at most 8% in the average Dice.


Subject(s)
Algorithms , Brain , Brain/diagnostic imaging , Magnetic Resonance Imaging/methods , Neuroimaging
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