Articulated Motion-Aware NeRF for 3D Dynamic Appearance and Geometry Reconstruction by Implicit Motion States.

We propose a self-supervised approach for 3D dynamic reconstruction of articulated motions based on Generative Adversarial Networks and Neural Radiance Fields. Our method reconstructs articulated objects and recover their continuous motions and attributes from an unordered, discontinuous image set. Notably, we treat motion states as time-independent, recognizing that articulated objects can exhibit identical motions at different times. The key insight of our approach utilizes generative adversarial networks to create a continuous implicit motion state space. Initially, we employ a motion network extracts discrete motion states from images as anchors. These anchors are then expanded across the latent space using generative adversarial networks. Subsequently, motion state latent codes are input into motion-aware neural radiance fields for dynamic appearance and geometry reconstruction. To deduce motion attributes from the continuously generated motions, we adopt a cluster-based strategy. We thoroughly evaluate and validate our method on both synthesized and real data, demonstrating superior fidelity in appearances, geometries, and motion attributes of articulated objects compared to state-of-the-art methods.

Electrogenerated chemiluminescence resonance energy transfer between luminol and MnO2 nanosheets decorated with Cu2O nanoparticles for sensitive detection of RNase H.

In the present work, a novel approach was developed for the preparation of Cu2O nanoparticle decorated MnO2 nanosheets (Cu2O@MnO2). Uniformly dispersed Cu2O nanocrystals were produced on the surface of MnO2 nanosheets by in situ reduction under refluxing conditions. The unique structure of the used MnO2 nanosheet support played a vital role in the preparation of such Cu2O@MnO2 nanocomposites. The electrogenerated chemiluminescence (ECL) resonance energy transfer can occur between the luminol/H2O2 system and Cu2O@MnO2 nanocomposites, resulting in a decrease of the ECL intensity, which can be used to fabricate an ECL sensor. Cu2O@MnO2 nanocomposite modified heterologous DNA/RNA duplexes were modified on the GCE to construct an ECL-RET system, leading to the decrease of ECL intensity. As a highly conserved damage repair protein, RNase H can specifically hydrolyze RNA in DNA/RNA strands to release Cu2O@MnO2 nanocomposites and recover the ECL signal. As a result, an "off-on" mode ECL sensor for sensitive RNase H assay was fabricated. Under the optimal conditions, the detection limit of RNase H is 0.0005 U mL-1, which is superior to other approaches. The proposed method provides a universal platform for monitoring RNase H, and exhibits great potential in bioanalysis.

Dual-potential electrochemiluminescence of single luminophore for detection of biomarker based on black phosphorus quantum dots as co-reactant.

Simultaneous cathodic and anodic electrochemiluminescence (ECL) emissions of needle-like nanostructures of Ru(bpy)32+ (RuNDs) as the only luminophore are reported based on different co-reactants. Cathodic ECL was attained from RuNDs/K2S2O8 system, while anodic ECL was achieved from RuNDs/black phosphorus quantum dots (BPQDs) system. Ferrocene attached to the hairpin DNA could quench the cathodic and anodic ECL simultaneously. Subsequently, the ECL signals recovered in the presence of tumor marker mucin 1 (MUC1), which made it possible to quantitatively detect MUC1. The variation of ECL signal was related linearly to the concentrations of MUC1 in the range 20 pg mL-1 to 10 ng mL-1, and the detection limits were calculated to 2.5 pg mL-1 (anodic system, 3σ) and 6.2 pg mL-1 (cathodic system, 3σ), respectively. The recoveries were 97.0%, 105%, and 95.2% obtained from three human serum samples, and the relative standard deviation (RSD) is 5.3%. As a proof of concept, this work realized simultaneous ECL emission of  a single luminophore, which initiates a new thought in biomarker ECL detection beyond the traditional ones. Simultaneous cathodic and anodic ECL emissions of RuNDs were reported based on different co-reactants. Ferrocene could quench the ECL emission in the cathode and the anode simultaneously. Thus, an aptasensor was constructed based on the variation of ECL intensity. As a proof of concept, this work realized simultaneous ECL emission of a single luminophore, which initiates a new thought in biomarker ECL detection beyond the traditional ones by avoiding the false positive signals.