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1.
Sci Rep ; 14(1): 9968, 2024 04 30.
Article in English | MEDLINE | ID: mdl-38693198

ABSTRACT

Sex is an essential part of life and is a basic demand for human beings. Coronary heart disease can have an impact on patients' sexual lives; however, not much attention has been paid to it in China, and few studies have been conducted on this topic. Therefore, this study used a qualitative approach to understand the sexual experience of patients after the illness, thus laying the foundation for the development of relevant measures. Semi-structured interviews were conducted with 14 patients. Descriptive phenomenological methods were employed to collect data and explore the sexual experience of patients with coronary heart disease. A total of 4 thematic groups, 9 themes, and 23 subthemes were extracted. The four thematic groups were independent and cross-influenced. In these groups, alterations in the sexual experience, including the change in sexual physiology and psychological state, were affected by the lack of knowledge, age, disease, and other factors. Furthermore, the patient's perception of sexuality affected the quality of sexual life after the illness. The sexual experience of patients with coronary heart disease and its influencing factors, such as age, disease factors, and lack of related knowledge, were described. The findings are expected to aid in formulating targeted and personalized intervention measures.


Subject(s)
Coronary Disease , Quality of Life , Sexual Behavior , Humans , Female , Male , Middle Aged , Coronary Disease/psychology , Aged , Sexual Behavior/psychology , Adult , Sexuality/psychology , China/epidemiology , Qualitative Research
2.
Phys Chem Chem Phys ; 25(2): 932-935, 2023 Jan 04.
Article in English | MEDLINE | ID: mdl-36511772

ABSTRACT

The photocurrent output of the C6H4NH2CuBr2I/TiO2 heterojunction photoelectrode in an aqueous solution is super stable even after 30 000 s. However, the photocurrent is extremely weak. Intensity-modulated photocurrent spectroscopy revealed that the electron transfer in the C6H4NH2CuBr2I/TiO2 photoelectrode without bias is not sufficiently fast to compete with the charge recombination process due to the short diffusion length (∼23 nm), resulting in a low photocurrent. The charge separation and charge transfer efficiency in the bulk of C6H4NH2CuBr2I could be significantly improved under a small reverse electric field (Er), resulting in an enhanced photocurrent.

3.
Neurosci Lett ; 738: 135401, 2020 11 01.
Article in English | MEDLINE | ID: mdl-32976920

ABSTRACT

Accumulating evidence suggests that abnormal fatty acid composition is related to the development of Alzheimer's disease (AD). However, there is no consistency in the fatty acid profile and metabolism associated with AD pathogenesis. This study aims to define the characteristics of fatty acid composition and metabolism in AD. Using 6-month-old APP/PS1 transgenic mice with wild-type mice as a control, we examined the serum lipids, brain fatty acid composition, and the expression levels of various genes involved in liver fatty acid ß-oxidation. The results of our study demonstrate that APP/PS1 mice present decreased serum free fatty acids, altered brain fatty acid profiles, and minimal change in liver fatty acid ß-oxidation. Our results suggest that abnormal fatty acid compositions and contents may play potential roles in AD progression. This study provides further evidence for the metabolic basis of AD pathogenesis.


Subject(s)
Amyloid beta-Peptides/metabolism , Brain/drug effects , Brain/metabolism , Fatty Acids/pharmacology , Amyloid beta-Peptides/drug effects , Amyloid beta-Protein Precursor/drug effects , Amyloid beta-Protein Precursor/genetics , Amyloid beta-Protein Precursor/metabolism , Animals , Disease Models, Animal , Disease Progression , Fatty Acids/metabolism , Mice
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