ABSTRACT
OBJECTIVE: To evaluate thyroid function and morphology in all diabetic outpatients from our institution. METHODS: From 1996 to 1998, all diabetic patients were submitted to thyroid ultrasonography (US) and serum measurement of free T4, TSH, TPOAB, and TRAb. The control group, encompassing outpatients of the same hospital without diabetes and thyroid diseases, was submitted to the same evaluation. A patient was shown to have thyroid disorder when two or more measurements were altered, or when the US was abnormal. RESULTS: The diabetic patients (n= 256) differed from controls (n= 75) by presenting a greater frequency of thyroid disorders (51.6% vs. 38.7%; P<0.05). In patients with thyroid disorders, both groups did not differ regarding thyroid function. In diabetic patients with thyroid disorders there was a higher frequency of women, type 2 diabetes, and family history of thyroid disorders. CONCLUSIONS: The high prevalence of thyroid disorders in the diabetic population leads us to recommend thyroid evaluations in all diabetic patients.
Subject(s)
Diabetes Mellitus, Type 1/complications , Diabetes Mellitus, Type 2/complications , Thyroid Diseases/epidemiology , Adolescent , Adult , Aged , Aged, 80 and over , Brazil/epidemiology , Case-Control Studies , Female , Goiter/diagnosis , Goiter/etiology , Humans , Male , Middle Aged , Outpatient Clinics, Hospital , Statistics, Nonparametric , Thyroid Diseases/diagnosis , Thyroid Diseases/etiology , Thyroid Function TestsABSTRACT
OBJETIVO: Avaliar morfológica e funcionalmente a tireóide de pacientes com diabetes mellitus (DM) acompanhados ambulatorialmente no Hospital das Clínicas de Botucatu. MÉTODOS: No período de 1996 a 1998, a todo paciente com DM, exceto os com tireopatia prévia, era solicitada dosagem sérica de T4L, TSH, anti-TPO e TRAb e ultra-sonografia (US) da tireóide. Diagnosticou-se tireopatia quando havia dois ou mais parâmetros séricos ou a US alterados. Procedeu-se igualmente com pacientes ambulatoriais da mesma Instituicão, sem DM e não-tireopatas prévios (controle). RESULTADOS: Os 256 pacientes com DM apresentaram maior freqüência de tireopatias que os 75 controles (51,6 por cento vs. 38,7 por cento; P<0,05). Entre os com tireopatias, ambos os grupos não diferiram quanto ao estado funcional da tireóide. Entre os pacientes com DM com e sem tireopatias, os primeiros apresentaram maior freqüência de mulheres, de DM tipo 2 e de história familiar de tireopatia. CONCLUSÕES: A elevada prevalência de tireopatias na populacão com DM conduz à recomendacão de avaliacão tireoidiana em todo paciente com DM.
