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1.
J Vet Intern Med ; 32(1): 433-440, 2018 Jan.
Article in English | MEDLINE | ID: mdl-29171090

ABSTRACT

BACKGROUND: A "high-sensitivity" cardiac troponin-T (hscTnT) assay recently has been validated for use in horses and is a specific biomarker of myocardial damage. Postexercise release kinetics of cTnT utilizing the hscTnT assay have yet to be established in horses. OBJECTIVES: To determine: (1) cTnT release kinetics in racing Thoroughbreds after a high-intensity 5/8th mile Chuckwagon race; (2) the effects of age on pre- and postrace cTnT concentrations; and (3) sampling guidelines for clinicians evaluating horses presenting after exercise. ANIMALS: Samples were obtained from 38 Thoroughbred geldings aged 5-16 years before racing and immediately, 2, 3, 4, 6, 12, and 24 hour postrace. METHODS: Prospective, observational study with convenience sampling. A fifth-generation hscTnT assay was used for plasma sample analysis, and concentrations were compared at all time-points. Correlations were determined between cTnT concentrations and age. Biochemistry analysis was performed to assess rhabdomyolysis, renal failure, and exercise-induced dehydration. RESULTS: All horses with measureable cTnT concentrations had significant postexercise increases in cTnT with a median peak (8.0 ng/L) at 3-hour postrace. All horses had peak postexercise cTnT concentrations 2- to 6-hour postrace ≤ the 99th percentile upper reference limit of 23.2 ng/L, after which all cTnT concentrations decreased until returning to baseline by 12-24 hours. There was no correlation over time between cTnT concentrations and age. CONCLUSIONS AND CLINICAL IMPORTANCE: In racing Thoroughbreds completing short-duration, high-intensity Chuckwagon races, cTnT concentrations are expected to be increased 2- to 6-hour postrace and to decrease by 12-24 hours while remaining ≤23.2 ng/L throughout. This study contributes to establishing guidelines for clinical use of the hscTnT assay in exercising horses.


Subject(s)
Horses/blood , Troponin T/blood , Age Factors , Animals , Biomarkers , Guidelines as Topic , Immunoassay/methods , Immunoassay/veterinary , Kinetics , Male , Physical Exertion/physiology , Prospective Studies , Running , Time Factors
2.
Astrophys J Lett ; 851(No 1)2017 Dec 10.
Article in English | MEDLINE | ID: mdl-29657703

ABSTRACT

We compare element and isotopic fractionations measured in solar wind samples collected by NASA's Genesis mission with those predicted from models incorporating both the ponderomotive force in the chromosphere and conservation of the first adiabatic invariant in the low corona. Generally good agreement is found, suggesting that these factors are consistent with the process of solar wind fractionation. Based on bulk wind measurements, we also consider in more detail the isotopic and elemental abundances of O. We find mild support for an O abundance in the range 8.75 - 8.83, with a value as low as 8.69 disfavored. A stronger conclusion must await solar wind regime specific measurements from the Genesis samples.

3.
Environ Entomol ; 45(5): 1115-1122, 2016 10.
Article in English | MEDLINE | ID: mdl-27477672

ABSTRACT

Onion thrips, Thrips tabaci Lindeman, is a significant pest of onion crops worldwide, but little is known about its patterns of aerial dispersal in the context of abiotic environmental factors. Thrips tabaci adults were passively collected from the air column above onion fields in western New York using clear sticky cards over a series of sampling periods in 2012, 2013, and 2014 while on-site weather conditions were recorded. Results indicated that T. tabaci adult densities on aerial traps during daylight averaged 279 times greater per hour than densities on similar traps at night. Adult dispersal also tended to spike during presunset, indicating that thrips initiated flight diurnally and within 1 h before sunset. Densities of T. tabaci on aerial traps increased significantly as temperature increased above 17 °C and 90% of the thrips were captured between 20.8 and 27.7 °C; no thrips were captured above 30.6 °C. Densities of T. tabaci on aerial traps decreased significantly as wind speed increased, with no thrips captured at winds exceeding 3.8 m/s (13.7 kph). In 2013 and 2014, T. tabaci densities on aerial traps prior to the passage of a cold front (relatively high atmospheric pressure and temperature with low wind speed) were significantly greater than densities after passage of the front, suggesting that T. tabaci disperses on synoptic weather systems.


Subject(s)
Animal Distribution , Onions , Thysanoptera/physiology , Weather , Animals , Crops, Agricultural/growth & development , New York , Onions/growth & development , Temperature , Wind
4.
BMC Vet Res ; 12(1): 104, 2016 Jun 13.
Article in English | MEDLINE | ID: mdl-27296016

ABSTRACT

BACKGROUND: Cardiac troponin-I assays have been validated in horses.'High-sensitivity' cardiac troponin assays are now the standard in human cardiology. OBJECTIVE: Appropriately validate the'high-sensitivity' cardiac Troponin-T (hscTnT) assay for clinical use in horses, establish reference intervals, determine the biological variation, and demonstrate assay utility in selected clinical cases. METHODS: Analytical validation of the Roche hscTnT assay included within- and between-run precision, linear dose response, limit of quantitation (LoQ), stability, and comparison with cTn-I (iSTAT). Reference intervals and biological variation were determined using adult, healthy, Non-Competition Horses (N = 125) and Racing-Thoroughbreds (N = 178). HscTnT levels were measured in two horses with cardiac pathology. RESULTS: The hscTnT demonstrates acceptable within-run (L1 = 6.5 ng/L, CV 14.9 %, L2 = 10.1 ng/L, CV 8.7 %, L3 = 15.3 ng/L, CV 5.4 %) and between-run precision (L1 = 12.2 ng/L, CV 8.4 %, L2 = 57.0 ng/L, CV 8.4 %, L3 = 256.0 ng/L, CV 9.0 %). The assay was linear from 3 to 391 ng/L. The LoQ was validated at 3 ng/L. Samples demonstrated insignificant decay over freeze-thaw cycle. Comparison with cTnI assay showed excellent correlation (range: 8.0-3535.0 ng/L, R(2) = 0.9996). Reference intervals: The upper 95(th) and 99(th) percentile of the hscTnT population distribution were 6.8 and 16.2 ng/L in Non-Competition Horses, and 14.0 and 23.2 ng/L in Racing-Thoroughbreds. Between-breed, diurnal effect, and between-day variation was below LoQ. Two clinical cases with presumed cardiac pathology had hscTnT levels of 220.9 ng/L and 5723.0 ng/L. CONCLUSIONS: This benchmark study is the first to comply with CLSI guidelines, thus further establishing the performance characteristics of the hscTnT assay, and reference intervals in healthy horses. Two clinical cases demonstrated further the clinical utility of the assay.


Subject(s)
Horses/blood , Immunoassay/veterinary , Troponin T/analysis , Animals , Female , Humans , Immunoassay/methods , Luminescent Measurements/veterinary , Male , Reference Values , Sensitivity and Specificity
5.
Environ Entomol ; 44(4): 921-30, 2015 Aug.
Article in English | MEDLINE | ID: mdl-26314037

ABSTRACT

Onion thrips, Thrips tabaci Lindeman, is a worldwide pest of onion whose feeding damage and transmission of Iris yellow spot virus (IYSV) may reduce onion yields. Little is known about the seasonal dynamics of T. tabaci dispersal, the distance of dispersal, or the movement of thrips infected with IYSV during the onion-growing season. To address these questions, T. tabaci adults were collected using transparent sticky card traps in commercial onion fields three times during the onion-growing season (June, July, and late August) at varying heights above the canopy (0.5-6 m above soil surface) and with trap-equipped unmanned aircraft (UAVs) flying 50-60 m above onion fields during August sampling periods in 2012 and 2013. Randomly selected subsamples of captured T. tabaci were tested for IYSV using RT-PCR. Most T. tabaci adults were captured in late August and near the onion canopy (<2 m) throughout the season. However, 4% of T. tabaci adults captured on sticky cards were at altitudes ≥2 m, and T. tabaci were also captured on UAV-mounted traps. These data strongly suggest that long-distance dispersal occurs. More T. tabaci captured on sticky cards tested positive for IYSV in August (53.6%) than earlier in the season (2.3 to 21.5% in June and July, respectively), and 20 and 15% of T. tabaci captured on UAV-mounted traps tested positive for IYSV in 2012 and 2013, respectively. Our results indicate that T. tabaci adults, including viruliferous individuals, engage in long-distance dispersal late in the season and likely contribute to the spread of IYSV.


Subject(s)
Animal Distribution , Thysanoptera/physiology , Thysanoptera/virology , Tospovirus/physiology , Animals , Female , Male , New York , Onions/physiology , Onions/virology
6.
Compr Psychiatry ; 54(5): 506-16, 2013 Jul.
Article in English | MEDLINE | ID: mdl-23375185

ABSTRACT

OBJECTIVE: The purpose of this investigation was to compare the latent structures of the interview (EDE) and questionnaire (EDE-Q) versions of the Eating Disorder Examination. METHODS: Participants were 280 children, adolescents, and young adults seeking eating disorder treatment. Two separate latent structure analyses (LSAs) were conducted; one used variables from the EDE as indicators and the other used the corresponding variables from the EDE-Q as indicators. RESULTS: The EDE and EDE-Q models both yielded four-class solutions. Three of the four classes from the EDE-Q model demonstrated moderate to high concordance with their paired class from the EDE model. Using the EDE-Q to detect the EDE, the sensitivity and specificity of measuring certain classes varied from poor (18.6%) to excellent (93.7%). The overall concordance was moderate (κ=.49). DISCUSSION: These data suggest that LSAs using the EDE and EDE-Q may be directly compared; however, differences between results may represent inconsistencies in response patterns rather than true differences in psychopathology.


Subject(s)
Feeding and Eating Disorders/diagnosis , Interview, Psychological , Surveys and Questionnaires , Adolescent , Adult , Child , Feeding and Eating Disorders/therapy , Female , Humans , Male , Psychiatric Status Rating Scales , Psychometrics , Sensitivity and Specificity
7.
Int J Eat Disord ; 45(5): 704-10, 2012 Jul.
Article in English | MEDLINE | ID: mdl-22331840

ABSTRACT

OBJECTIVE: This study investigated the use and frequency of multiple methods of compensatory behaviors and how they relate to eating-related and general psychopathology for youth with eating disorders (ED). METHOD: Participants were 398 referrals to a pediatric ED treatment program (91.2% female; M age = 14.9 ± 2.2). ANOVA and chi-square tests compared participants reporting multiple methods of compensatory behaviors, single method of compensatory behaviors, and no compensatory behaviors on measures of ED and general psychopathology. Partial correlations examined associations between compensatory behavior, frequency and severity of ED and general psychopathology. RESULTS: Participants reporting multiple methods of compensatory behaviors had significantly greater ED and general psychopathology than the other groups (ps < .001). Frequency of compensatory behaviors was associated with ED psychopathology (partial r = .14; p = .007) but not with general psychopathology. DISCUSSION: Engaging in multiple methods of compensatory behaviors is related to greater ED and general psychopathology, whereas frequency is only related to greater ED symptom severity.


Subject(s)
Feeding and Eating Disorders/psychology , Severity of Illness Index , Adolescent , Child , Depression/diagnosis , Depression/psychology , Feeding and Eating Disorders/diagnosis , Feeding and Eating Disorders/therapy , Female , Humans , Male , Self Concept , Surveys and Questionnaires
8.
Int J Eat Disord ; 45(7): 850-5, 2012 Nov.
Article in English | MEDLINE | ID: mdl-21826696

ABSTRACT

OBJECTIVE: The diagnostic concordance of the interview (EDE) and questionnaire (EDE-Q) versions of the Eating Disorder Examination was examined. METHOD: Two-hundred seventeen patients seeking eating disorder treatment completed the EDE and EDE-Q before beginning treatment. Diagnostic algorithms were generated for the Diagnostic and Statistical Manual of Mental Disorders, fourth edition, text revision (DSM-IV-TR) and proposed Diagnostic and Statistical Manual of Mental Disorders (DSM-5) criteria using data first from the EDE and then from the EDE-Q; thus, each participant received four diagnoses. RESULTS: The sensitivity of the EDE-Q for individual diagnoses ranged from 27.8% to 84.3% (DSM-IV-TR) and from 36.8% to 80.8% (DSM-5). The specificity of the EDE-Q for individual diagnoses ranged from 71.1% to 98.5% (DSM-IV-TR) and from 77.3% to 98.0% (DSM-5). The overall diagnostic concordance was moderate (κ = .57-.60). DISCUSSION: The proposed DSM-5 criteria improved the diagnostic concordance of the two instruments and reduced the prevalence of Eating Disorder Not Otherwise Specified (EDNOS). However, concordance improvement was modest and both instruments still diagnosed most respondents with EDNOS.


Subject(s)
Feeding and Eating Disorders/diagnosis , Interview, Psychological , Surveys and Questionnaires , Adolescent , Adult , Child , Female , Humans , Male , Middle Aged , Psychiatric Status Rating Scales , Sensitivity and Specificity
9.
Eat Behav ; 12(4): 328-31, 2011 Dec.
Article in English | MEDLINE | ID: mdl-22051370

ABSTRACT

PURPOSE: This study evaluated the prevalence and clinical significance of driven exercise (DE) in treatment-seeking youth. METHODS: Participants were 380 consecutive referrals to a pediatric eating disorder program (90.8% female; M age=14.9±2.2). Spearman's rho correlations examined the relation between DE frequency, and Beck Depression Inventory (BDI) and Eating Disorders Examination (EDE) Global Severity scores. ANOVA compared those reporting only DE, only vomiting, or both DE and vomiting on the aforementioned measures. RESULTS: 51.3% of participants (n=193) reported DE in the past 3 months, with an average of 21.8 (SD=32.6) episodes. Frequency of DE was related to EDE global severity score (Spearman's rho=.46; p<.001) and BDI Total Score (Spearman's rho=.33; p<.001). Participants reporting both vomiting and DE had the highest EDE global severity and BDI total scores. CONCLUSIONS: DE is associated with greater eating disorder and depressive symptomatology, especially when paired with vomiting. The findings highlight the importance of assessing for DE in youth presenting for eating disorder treatment.


Subject(s)
Compulsive Behavior/psychology , Depression/psychology , Drive , Exercise/psychology , Feeding and Eating Disorders/psychology , Adolescent , Body Mass Index , Chicago , Child , Compulsive Behavior/diagnosis , Cross-Sectional Studies , Depression/diagnosis , Depression/epidemiology , Feeding and Eating Disorders/diagnosis , Feeding and Eating Disorders/epidemiology , Female , Hospitals, University , Humans , Male , Psychiatric Status Rating Scales , Severity of Illness Index , Sex Distribution , Statistics, Nonparametric , Vomiting
10.
J Perinatol ; 29(9): 591-9, 2009 Sep.
Article in English | MEDLINE | ID: mdl-19262569

ABSTRACT

OBJECTIVE: To characterize hospital-acquired bloodstream infection rates among New York State's 19 regional referral NICUs (at regional perinatal centers; RPCs) and develop strategies to promote best practices to reduce central line-associated bloodstream infections (CLABSIs). STUDY DESIGN: During 2006 and 2007, RPC NICUs reported bloodstream infections, patient-days and central line-days to the Department of Health, and shared their results. Aiming to improve, participants created a central line-care bundle based on visiting a potentially best performing NICU and reviewing the literature. RESULT: All 19 RPCs participated in this quality initiative, contributing 218,096 patient-days and 56,911 central line-days of observation. Individual RPC nosocomial sepsis infection (NI) rates ranged from 1.0 to 5.8 NIs per 1000 patient-days (2006), and CLABSI rates ranged from 2.6 to 15.1 CLABSIs per 1000 central line-days (2007). A six-fold rate variation among RPC NICUs was observed. Participants unanimously approved a level-1 evidence-based central line-care bundle. CONCLUSION: Individual RPC rates and consequent morbidity and resource use attributable to these infections were substantial and varied greatly. No center was without infections. It is hoped that the cooperation and accountability exhibited by the RPCs will result in a major network for characterizing performance and improving outcomes.


Subject(s)
Catheter-Related Infections/prevention & control , Cross Infection/prevention & control , Quality Indicators, Health Care , Sepsis/prevention & control , Benchmarking , Catheterization, Central Venous/standards , Hand Disinfection/standards , Humans , Infant, Extremely Low Birth Weight , Infant, Newborn , Intensive Care Units, Neonatal , New York
11.
Braz J Med Biol Res ; 41(8): 709-15, 2008 Aug.
Article in English | MEDLINE | ID: mdl-18797706

ABSTRACT

The purpose of this study was to examine the effects of an exercise intervention on the total caloric intake (TCI) of breast cancer patients undergoing treatment. A secondary purpose was to determine whether or not a relationship existed between changes in TCI, body fat composition (%BF), and fatigue during the study, which lasted 6 months. Twenty females recently diagnosed with breast cancer, scheduled to undergo chemotherapy or radiation, were assigned randomly to an experimental (N = 10) or control group (N = 10). Outcome measures included TCI (3-day food diary), %BF (skinfolds), and fatigue (revised Piper Fatigue Scale). Each exercise session was conducted as follows: initial cardiovascular activity (6-12 min), followed by stretching (5-10 min), resistance training (15-30 min), and a cool-down (approximately 8 min). Significant changes in TCI were observed among groups (F1,18 = 8.582; P = 0.009), at treatments 2 and 3, and at the end of the study [experimental (1973 +/- 419), control (1488 +/- 418); experimental (1946 +/- 437), control (1436 +/- 429); experimental (2315 +/- 455), control (1474 +/- 294), respectively]. A significant negative correlation was found (Spearman rho(18) = -0.759; P < 0.001) between TCI and %BF and between TCI and fatigue levels (Spearman rho(18) = -0.541; P = 0.014) at the end of the study. In conclusion, the results of this study suggest that an exercise intervention administered to breast cancer patients undergoing medical treatment may assist in the mitigation of some treatment side effects, including decreased TCI, increased fatigue, and negative changes in body composition.


Subject(s)
Adipose Tissue/metabolism , Body Composition/physiology , Breast Neoplasms/rehabilitation , Energy Intake/physiology , Exercise/physiology , Adult , Aged , Breast Neoplasms/metabolism , Breast Neoplasms/therapy , Exercise Test/methods , Fatigue/rehabilitation , Female , Humans , Middle Aged , Physical Endurance/physiology
12.
Braz. j. med. biol. res ; 41(8): 709-715, Aug. 2008. graf, tab
Article in English | LILACS | ID: lil-491921

ABSTRACT

The purpose of this study was to examine the effects of an exercise intervention on the total caloric intake (TCI) of breast cancer patients undergoing treatment. A secondary purpose was to determine whether or not a relationship existed between changes in TCI, body fat composition ( percentBF), and fatigue during the study, which lasted 6 months. Twenty females recently diagnosed with breast cancer, scheduled to undergo chemotherapy or radiation, were assigned randomly to an experimental (N = 10) or control group (N = 10). Outcome measures included TCI (3-day food diary), percentBF (skinfolds), and fatigue (revised Piper Fatigue Scale). Each exercise session was conducted as follows: initial cardiovascular activity (6-12 min), followed by stretching (5-10 min), resistance training (15-30 min), and a cool-down (approximately 8 min). Significant changes in TCI were observed among groups (F1,18 = 8.582; P = 0.009), at treatments 2 and 3, and at the end of the study [experimental (1973 ± 419), control (1488 ± 418); experimental (1946 ± 437), control (1436 ± 429); experimental (2315 ± 455), control (1474 ± 294), respectively]. A significant negative correlation was found (Spearman rho(18) = -0.759; P < 0.001) between TCI and percentBF and between TCI and fatigue levels (Spearman rho(18) = -0.541; P = 0.014) at the end of the study. In conclusion, the results of this study suggest that an exercise intervention administered to breast cancer patients undergoing medical treatment may assist in the mitigation of some treatment side effects, including decreased TCI, increased fatigue, and negative changes in body composition.


Subject(s)
Adult , Aged , Female , Humans , Middle Aged , Adipose Tissue/metabolism , Body Composition/physiology , Breast Neoplasms/rehabilitation , Energy Intake/physiology , Exercise/physiology , Breast Neoplasms/metabolism , Breast Neoplasms/therapy , Exercise Test/methods , Fatigue/rehabilitation , Physical Endurance/physiology
13.
Vascular ; 12(4): 271-2, 2004.
Article in English | MEDLINE | ID: mdl-15704323

ABSTRACT

Thigh compartment syndrome is uncommon and may go unrecognized. Signs and symptoms include a history of thigh swelling and/or hematoma and pain after minor injury in a patient who is anticoagulated. Surgical approaches to the deep thigh compartments are described.


Subject(s)
Compartment Syndromes/diagnosis , Thigh , Aged , Compartment Syndromes/complications , Compartment Syndromes/surgery , Fasciotomy , Hematoma/etiology , Hematoma/surgery , Humans , Male , Middle Aged , Thigh/injuries , Thigh/surgery , Treatment Outcome
14.
J Craniofac Genet Dev Biol ; 20(1): 1-9, 2000.
Article in English | MEDLINE | ID: mdl-10879652

ABSTRACT

In the assessment of human origins, chimpanzees (Pan troglodytes, henceforth called Pan) represent the best hominoid outgroup for comparisons. Such an outgroup roots the "anatomically modern" human population cluster, or continuum. This study incorporates chimpanzees into a worldwide modern human database of quantified complete tooth variables (approximately 30 per tooth; e.g., root, pulp, enamel) in an attempt to develop a more accurate phylogeny of the hominoid continuum, with only intervening extinct hominids missing. Canonical discriminate analysis was performed mainly among Liberian common chimpanzees and global samples of humans. The first canonical variable explained 70% of the total variance and showed a tight cluster of humans, with chimpanzees as a distant outgroup. Within the human community, first non-San Bushman, sub-Saharan Africans and Andamanese, and then, close in, Australian aborigines were positioned towards Pan. Their relative orientation suggested an African human origin with the first branch within sub-Saharan Africa: sub-Saharan Africans and San Bushmen. Next, Andamanese Negritos, and then Australian aborigines, formed the early first surviving modern human lineage to leave Africa. Thin enamel and big teeth with relatively large roots characterized Pan nonmolar teeth. Humans showed a generalized sexual dimorphism for all teeth, with males having bigger teeth, bigger relative roots, and thinner enamel than females, while only Pan canines had significant and impressive sexual dimorphism. Interestingly, Pan molars were not larger than human molars. The data suggest that although hominids underwent two dental macroevolutionary events, the lineage leading to modern humans only experienced anterior tooth-size reduction. The suggested evolutionary significance of the observed total tooth variation is discussed.


Subject(s)
Evolution, Molecular , Pan troglodytes/genetics , Tooth/physiology , Analysis of Variance , Animals , Biological Evolution , Female , Humans , Male , Molar/physiology , Multivariate Analysis , Phylogeny , Sex Factors
15.
J Dent Res ; 79(1): 13-20, 2000 Jan.
Article in English | MEDLINE | ID: mdl-10690655

ABSTRACT

Dental anthropology is a key discipline in studies to determine the evolutionary history of our hominid ancestors, to identify the origin and dispersal of modern humans, and to reconstruct the source of observed dental variation. A survey of hominid and modern human evolutionary history, emphasizing results from powerful multivariate dental morphometric methodologies, suggests a single African origin of modern humans > 150,000 years before present from a Homo heidelbergensis ancestor. A continuum among modern humanity is described, with, first, sub-Saharan Africans, then southeast Asian Negrito, and Australian aborigines at its extant root. Other interpretations of the available data are possible. Examinations of the progress of the evolution of teeth through time give significant insight into dental morphogenetics and variation, and the biology of dental evolution. The mechanisms of evolution which fashion a phenotype and the methods of molecular and dental phylogenetics are reviewed and evaluated. This is an exciting time for dental anthropology, with fascinating and challenging questions to address, but anthropologists, not dentists, dominate the field. The perspective of a dentist can meaningfully add to the dynamics of dental anthropology.


Subject(s)
Anthropology , Dentistry , Animals , Biological Evolution , Hominidae/anatomy & histology , Humans , Linguistics , Molecular Biology , Phylogeny , Tooth/anatomy & histology
16.
Am J Phys Anthropol ; 111(3): 425-7, 2000 Mar.
Article in English | MEDLINE | ID: mdl-10685040

ABSTRACT

The anatomic distribution of the Stafne static mandibular bone defect (SSBD) is extended with a description of a cavitation defect on the buccal ramus of the mandible. The anatomical placement of SSBD thus correlates precisely with the submandibular and parotid salivary glands, and gives further evidence that an increase in major salivary gland size is associated with the defect. The global latitudinal variation in the population prevalence of SSBD ranges from 10% in the tropics to virtually 0% in most of the arctic. Globally the defect directly correlates with parasite load and diversity, and may be a marker for of a history of an environment with high levels of enteric macroparasite infestation.


Subject(s)
Mandible/abnormalities , Mandibular Diseases/pathology , Anthropology, Physical , Environment , Humans , Mandibular Diseases/epidemiology , Prevalence , Reference Values , Salivary Glands/anatomy & histology
17.
J Craniofac Genet Dev Biol ; 19(3): 119-27, 1999.
Article in English | MEDLINE | ID: mdl-10589393

ABSTRACT

Recent genetic studies have heightened the expectation that the origin of modern humans will be defined, but one clear vision has yet to be developed. The study of teeth has historically been an informative means to help define human dispersals. Quantitative tooth data is presented encompassing worldwide human populations. A null hypothesis phylogeny developed from the multivariate analysis of the microevolution of the dental phenotype was interpreted to be broadly in accord with the dominant interpretation of genetic, archaeological, and other dental data by showing that the first division in the dispersion of extant humanity was within sub-Sahara Africans; i.e., San, and Western Africans and Bantu. This "out-of-Africa" interpretation of the graphical results suggests that the first modern human African emigrants not to go extinct were Southeast Asian Negritos. All Eurasians then emerged and expanded through a series of extinct antecedent populations branching from the short lineage extending from Negritos to Australian aborigines. Caucasoids were the first group to fission from this stock. Under this hypothesis, the next to have emerged were antecedent Southeast Asians, from which present Southeast Asians and then antecedent east Central Asians then diverged. Independently, people from the region of Mongolia and all Native Americans arose as daughter populations from antecedent east Central Asians. The broad outline of humanity studied here cannot disprove the equally explanatory protean multiregional hypotheses, but with the inclusion of hominids and further modern human populations either parts of the multiregional hypothesis or the outlined more linear evolutionary scenario likely can be refuted.


Subject(s)
Biological Evolution , Phylogeny , Racial Groups , Tooth/anatomy & histology , Emigration and Immigration , Female , Humans , Male , Models, Statistical , Multivariate Analysis , Odontometry , Paleodontology , Phenotype
18.
J Thorac Cardiovasc Surg ; 117(3): 419-28; discussion 428-30, 1999 Mar.
Article in English | MEDLINE | ID: mdl-10047643

ABSTRACT

BACKGROUND: It has been known for nearly 20 years that, in cardiovascular operations, a significant inverse relationship exists between clinical outcomes and the volume of procedures performed. Interestingly, this relationship persists 2 decades after it was recognized. OBJECTIVE: The purpose of this study was to examine the relationship between hospital volume and in-hospital deaths in 3 cardiovascular procedures: coronary artery bypass grafting, elective repair of abdominal aortic aneurysms, and repair of congenital cardiac defects. METHODS: The database includes all patients who were hospitalized in New York State during the years 1990 to 1995. Using standard logistic regression techniques, we analyzed the relationship between hospital volume and outcome. RESULTS: No correlation exists between hospital volume and in-hospital deaths in coronary artery bypass grafting. Statewide, 31 hospitals performed 97,137 operations over the 6-year period (overall mortality rate, 2. 75%). By contrast, most of the hospitals statewide (195 of 230 hospitals) performed 9847 elective abdominal aortic aneurysm repairs with an overall mortality rate of 5.5%. In abdominal aortic aneurysm operations, a significant inverse relationship between hospital volume and in-hospital deaths was determined. Sixteen hospitals performed 7199 repairs for congenital cardiac defects. A significant inverse relationship (which was most pronounced for neonates) was found between volume and death. CONCLUSIONS: The importance of these findings lies in the rather striking difference between the volume-outcome relationship found for operations for abdominal aortic aneurysms and congenital cardiac defects and the lack of such a relationship for coronary artery bypass grafting. This observation may be largely explained by the quality improvement program in New York State for bypass operations since 1989. If so, these results have important implications for expanding the scope of quality improvement efforts in New York State.


Subject(s)
Aortic Aneurysm, Abdominal/surgery , Coronary Artery Bypass/statistics & numerical data , Heart Defects, Congenital/surgery , Hospital Mortality , Adolescent , Adult , Aortic Aneurysm, Abdominal/mortality , Cardiac Surgical Procedures/statistics & numerical data , Child , Child, Preschool , Coronary Artery Bypass/mortality , Female , Heart Defects, Congenital/mortality , Humans , Infant , Infant, Newborn , Male , New York/epidemiology , Outcome Assessment, Health Care , Vascular Surgical Procedures/statistics & numerical data
19.
Adolescence ; 34(135): 503-21, 1999.
Article in English | MEDLINE | ID: mdl-10658858

ABSTRACT

This study examined verbal intimidation (VI), physical intimidation (PI), and physical violence (PV) in high school athletics, both by program and by sport. Antecedents were identified via principal component analysis; they included contextual setting, attitude, pressure, and coaching. Multiple regression analysis was used to assess relationships between antecedents and VI, PI, and PV. Coaching was the only significant predictor in 9 of 15 regression analyses of overall VI, PI, and PV, and one of two significant predictors in 4 of 6 additional analyses. Coaching was the only significant predictor of VI in basketball and football, PI in football and soccer, and PV in basketball and soccer. In addition to coaching, contextual setting was a significant predictor of PI in basketball, attitude was a significant predictor of PV in football, and pressure was a significant predictor of VI in soccer. The implications of these findings are discussed.


Subject(s)
Dominance-Subordination , Psychology, Adolescent , Sports/psychology , Violence/psychology , Adolescent , Aggression/psychology , Humans , Male , Social Facilitation
20.
J Athl Train ; 34(1): 19-24, 1999 Jan.
Article in English | MEDLINE | ID: mdl-16558542

ABSTRACT

OBJECTIVE: To assess, through exploratory research, 1) collegiate coaches' knowledge of eating disorders, 2) the confidence of collegiate coaches in their response correctness to questions about eating disorders among athletes, and 3) demographic data related to prior education about eating disorders and the role of the athletic department in providing such educational experiences. DESIGN AND SETTING: We distributed a 2-part questionnaire to 258 NCAA Division I-A coaches from 5 universities selected by sampling convenience. SUBJECTS: One hundred thirty-eight collegiate coaches responded to the questionnaire for a response rate of 53.5%. MEASUREMENTS: Our survey consisted of 30 true-false questions that tested knowledge of eating disorders overall and in 5 domains. These domains included etiology, identifying signs and symptoms, management and treatment, risk factors, and education and prevention of eating disorders. Coaches indicated their level of certainty in their responses by rating their confidence level on a 4-item Likert-type scale. Demographic data focused on educational programs attended by coaches and teams. Descriptive statistics were used to analyze all data. RESULTS: Our results suggest a need for coaches to achieve a greater knowledge of eating disorders in all domains. Evidence showed that educational programs about eating disorders were not often sponsored by the athletic department for coaches or athletes. There seemed to be poor communication between athletic departments and coaches regarding the availability of eating disorder educational resources. CONCLUSIONS: Data suggested coaches could benefit from comprehensive education in all domains of eating disorders; however, further study is needed to validate these findings, to determine the actual effectiveness of education in the prevention of eating disorders, and to differentiate coaches' knowledge specific to sport coached and to coach and team sex.

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