ABSTRACT
The procedure for measuring cardiac output and circulating blood volume is based on blood ability to modify its electrical conductance due to the amount of introduced ions (0.9% sodium chloride solution) or undissociated molecules (5% glucose solution). The cardiac output and circulating blood volume were calculated after measuring an area under the electrical impedance indicator dilution curve using the given formulas. With the described and thermodilution methods, the cardiac output was compared (r = 0.95). The correlation factor with the radioisotopic method in measuring the circulating blood volume was 0.88. Clinical investigations carried out in 47 patients on a programmed hemodialysis showed a significant decrease in cardiac output approximately by 700 ml/mi (7.9%) and circulating blood volume by an average of 900 ml (15.2%) by the end of a hemodialysis session, the rate of the circulating blood volume to body weight being also decreased. There was a predominant fluid "release" from the vascular bed.
Subject(s)
Hemodynamics/physiology , Renal Dialysis , Blood Volume/physiology , Cardiac Output/physiology , Electric Conductivity/physiology , Humans , Indicator Dilution Techniques , Kidney Failure, Chronic/physiopathology , Kidney Failure, Chronic/therapyABSTRACT
The article discusses the results of study of the cardiac output (CO) and circulation blood volume (CBV) in patients at the beginning and end of hemodialysis. The dynamics of changes of these parameters during hemodialysis was studied in 31 patients (42 sessions). The CO and CBV reduced significantly. In a group of 10 patients who felt worse, the CO reduced by more than 30 per cent in 7, the CBV diminished by 25 and 30 per cent in 2, and CBV and CO reduced by more than 30 per cent in 1 patient in relation to the initial level. The CO and CBV were measured by means of the method of dilution of electroimpedance indicators.
