Subject(s)
Food Inspection/methods , Food/standards , Food Microbiology , Food Services/standards , Nutritive Value , USSRABSTRACT
With albino rats fed on beef irradiated raw with gamma-rays in a dose of 0.6 Mrad (given to animals cooked) and on fried meat irradiated with gamma-rays in a dose of 0.8 Mrad the mutagenic properties of these products and their effect on the sexual glands of male-rats were studied. The mutagenic activity of the irradiated meat products was assessed with reference to induction of dominant lethal mutations, the gonadotropic effect being judged about by the functional state of the sexual glands in the male rats. Within the limit of described experiment no mutagenic and gonadotropic influence of the irradiated study products was detected.
Subject(s)
Fetal Death/etiology , Meat/toxicity , Mutagens , Animals , Cooking , Female , Gamma Rays , Genes, Dominant , Genes, Lethal , Male , Meat/radiation effects , Mutation , Pregnancy , RatsABSTRACT
Male-rats (25--27 g) were given perorally extracts separated from potato subjected to gamma-radiation in a dose of 10 krads (test groups) and from nonirradiated tubers (controls). The extracts were introduced for a period of one week, daily in an amount of 1 ml. The male from the test groups (each numbering 8--10 animals) received extracts of the raw potato stored for 4 months after irradiation and of the potato subjected to thermal treatment (cooking) after 1 day, 1 and 4 months of its storage. The frequency of chromosomal aberrations in the bone marrow cells was determined by the anaphase method. Altogether about 34 thous. cells (500-600 from each animal) were counted. The results testified to a significantly reduced frequency of chromosomal aberrations (bridges and fragments) occurring in the bone marrow cells of the mice which received extracts from the raw stored irradiated potato and from thermally treated freshly irradiated tubers, as compared to extracts obtained from the raw freshly irradiated potatoes. The extracts of irradiated potato cooked after 1 and 4 month of storage did not display any mutagenic properties.