[The effect of hemocarbosorption and biohemosorption on oxygen metabolism and intoxication in patients with peritonitis in multiple organ failure]. / Vliianie gemokarbosorbtsii i biogemosorbtsii na kislorodnyi obmen i intoksikatsiiu u bol'nykh s peritonitom pri poliorgannoi nedostatochnosti.

An analysis of results of treatment of patients with diffuse peritonitis has shown that the syndrome of polyorganic insufficiency is found in 24.2% of cases. A system of score screening assessment of severity of the course of polyorganic insufficiency syndrome has been developed. The dynamics of indicators of intoxication and oxygen metabolism was used for comparison of efficiency of hemosorption and biohemosorption. Conclusions are made that hemocarbosorption is preferable at the first phase of the syndrome of polyorganic insufficiency while biohemosorption--at the second phase of polyorganic insufficiency.

[The treatment of unformed intestinal fistulae]. / Lechenie nesformirovannykh kishechnykh svishchei.

Experience in the treatment of 33 patients with unformed intestinal fistulas is discussed. The choice of the method for surgical management was determined by the localization of the fistulas, the possibility of their occlusion, and the severity of the patient's condition. Complex therapy included selective administration of antibacterial agents and extracorporeal detoxification by means of biohemosorption. Rational surgical tactics and complex treatment including extracorporeal detoxification in patients with unformed external intestinal fistulas made it possible to reduce the mortality rate from 33.4% to 21.2% (7 patients died).

[Characteristics of the causative agent and of the immunological status of the body in experimental dormant staphylococcal infection]. / Kharakteristika vozbuditelia i immunologicheskogo statusa organizma pri dremliushchei stafilokokkovoi infektsii v ékspekimente.

Pathogenic staphylococci were found to persist in the focus of dormant infection in guinea pigs till day 100 of the experiment without changing their biological properties and sensitivity to antibiotics. The latent period of dormant staphylococcal infection was characterized by the increasing titers of antibodies to staphylococcal autostrains, by the positive results of the intradermal allergic test and the macrophage migration inhibition test with hemolytic staphylococcal allergen, as well as by the suppression of serum lysozyme activity. No changes in the content of complement and the total bactericidal activity of blood serum were detected.

[Causes and prevention of latent infection in abdominal surgery]. / Prichiny i profilaktika dremliushchei infektsii v abdominal'noi khirurgii.

The analysis of repeated admission of patients with purulent complications of wounds and cicatrices (261 patients) has shown that 24% of the patients had a latent infection which could manifest itself against the background of characteristic changes in the natural resistance of the organism. The main microbe isolated in the outbursts of latent infections was found to be pathogenic staphilococcus with endogenous introduction of microbes into tissues. The latent infection is believed by the author to play an important role in pathogenesis of purulent complications after operations associated with an injury of scarry tissues. Prophylactic and curative recommendations made by the author are described.