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J Antibiot (Tokyo) ; 71(4): 432-437, 2018 03.
Article in English | MEDLINE | ID: mdl-29402997

ABSTRACT

Two new compounds, robillafuran and (+)-robillapyrone, were isolated from the culture extract of a fungal strain of Robillarda along with (+)-monascuspyrone. The absolute configuration of (+)-robillapyrone and (+)-monascuspyrone was determined by ECD calculation. These three compounds showed preadipocyte differentiation activity at 10-40 µM.


Subject(s)
Anti-Bacterial Agents/isolation & purification , Anti-Bacterial Agents/pharmacology , Xylariales/metabolism , Adipocytes/drug effects , Cell Differentiation/drug effects , Humans , Magnetic Resonance Spectroscopy , Molecular Conformation , Plants/microbiology , Spectrometry, Mass, Electrospray Ionization , Spectrophotometry, Ultraviolet , Xylariales/chemistry
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