Subject(s)
Breast Neoplasms/diagnostic imaging , Breast Neoplasms/secondary , Carcinoma, Squamous Cell/diagnostic imaging , Carcinoma, Squamous Cell/secondary , Tongue Neoplasms/pathology , Citrates/pharmacokinetics , Female , Gallium/pharmacokinetics , Gallium Radioisotopes/pharmacokinetics , Humans , Middle Aged , Radionuclide Imaging , Radiopharmaceuticals/pharmacokineticsABSTRACT
We describe a case of jugular foramen chordoma with extracranial extension into the carotid, parapharyngeal, and perivertebral spaces through the jugular foramen. Although this type of extension is unusual, the differential diagnosis of head and neck tumors includes unusual extension of chordoma as well as extension of meningioma and neurinoma from the posterior skull base.
Subject(s)
Chordoma/diagnosis , Head and Neck Neoplasms/diagnosis , Magnetic Resonance Imaging , Skull Base Neoplasms/diagnosis , Temporal Bone/pathology , Tomography, X-Ray Computed , Aged , Carotid Arteries , Chordoma/diagnostic imaging , Diagnosis, Differential , Female , Head and Neck Neoplasms/diagnostic imaging , Humans , Jugular Veins , Meningioma/diagnosis , Neoplasm Invasiveness , Neurilemmoma/diagnosis , Pharynx , Skull Base Neoplasms/diagnostic imaging , Spine , Temporal Bone/diagnostic imagingABSTRACT
We present a postmastectomy patient in whom a mass was palpated in the chest wall. It appeared to be difficult to determine whether the chest wall mass was local recurrence of breast cancer or granulation induced by mastectomy on computed tomography (CT). The mass was successfully demonstrated on 99mTc-methoxyisobutylisonitrile (99mTc-MIBI) scintigraphy as an area of increased accumulation, and was considered to be a recurrent tumor. Surgical resection was performed, and the mass was histopathologically proven to be recurrence. 99mTc-MIBI scintigraphy may contribute to the detection of local recurrence or distant metastasis in addition to the diagnosis of primary breast cancer and axillary metastasis.
Subject(s)
Breast Neoplasms/diagnostic imaging , Neoplasm Recurrence, Local/diagnostic imaging , Radiopharmaceuticals , Technetium Tc 99m Sestamibi , Breast Neoplasms/surgery , Female , Humans , Mastectomy, Modified Radical , Middle Aged , Radionuclide ImagingABSTRACT
SUMMARY: We developed new embolic drug delivery emulsions to be utilized for malignant neoplasms. We combined additional water-soluble contrast materials (Ioxaglic acid, Iopamidol) with Glyceol, Poloxamer-188, or D-Mannitol to antitumor agent Lipiodol ultrafluid in order to generate stable emulsions. Some of these emulsions have been shown to cause pulmonary embolism in rabbits and to allow gradual diffusion of the antitumor agent in vitro. Good therapeutic utility is indicated. In particular, one emulsion containing D-Mannitol (Mizonokuchi emulsion), is expected to prolong drug delivery in malignant brain tumors.
ABSTRACT
Ferric ammonium citrate (FAC) can be used as a negative contrast agent on T2- weighted images, with the use of a high concentration resulting in a significant T2 shortening effect. Ten healthy volunteers underwent MR cholangiography (MRC) using Turbo Spin Echo. High-concentration FAC was administered at a normal dosage, but was diluted in a smaller amount of water than usual. Although all precontrast images showed high intensity intestinal fluid, which aggravated visualization of the bile duct, all postcontrast images obtained 6 to 14 minutes after administration showed blackening out of the fluid, improving the overall image quality of MRC.
Subject(s)
Bile Ducts/pathology , Contrast Media , Ferric Compounds , Magnetic Resonance Imaging/methods , Quaternary Ammonium Compounds , Adult , Female , Humans , Male , SolutionsABSTRACT
Various concentrations of ferric ammonium citrate (FAC) solution were scanned with conventional SE, Turbo SE (TSE) and STIR sequences on a 0.5-T MR unit. High-concentration FAC solution showed significant signal loss on T2-weighted images. Signal loss was more prominent on heavily T2-weighted images with longer TR/TE using the TSE sequence. T1-weighted images did not show significant signal loss even with high-concentration solution. On STIR images, remarkable signal loss occurred at twice the concentration that had a T1 value similar to fat. We concluded that high-concentration FAC solution may employ as a negative contrast agent in upper abdominal MR imaging.
