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1.
Article in English | MEDLINE | ID: mdl-37995159

ABSTRACT

Although studies on terrain identification algorithms to control walking assistive devices have been conducted using sensor fusion, studies on transition classification using only electromyography (EMG) signals have yet to be conducted. Therefore, this study was to suggest an identification algorithm for transitions between walking environments based on the entire EMG signals of selected lower extremity muscles using a deep learning approach. The muscle activations of the rectus femoris, vastus medialis and lateralis, semitendinosus, biceps femoris, tibialis anterior, soleus, medial and lateral gastrocnemius, flexor hallucis longus, and extensor digitorum longus of 27 subjects were measured while walking on flat ground, upstairs, downstairs, uphill, and downhill and transitioning between these walking surfaces. An artificial neural network (ANN) was used to construct the model, taking the entire EMG profile during the stance phase as input, to identify transitions between walking environments. The results show that transitioning between walking environments, including continuously walking on a current terrain, was successfully classified with high accuracy of 95.4 % when using all muscle activations. When using a combination of muscle activations of the knee extensor, ankle extensor, and metatarsophalangeal flexor group as classifying parameters, the classification accuracy was 90.9 %. In conclusion, transitioning between gait environments could be identified with high accuracy with the ANN model using only EMG signals measured during the stance phase.


Subject(s)
Deep Learning , Humans , Electromyography , Walking/physiology , Muscle, Skeletal/physiology , Gait/physiology , Algorithms
2.
Front Bioeng Biotechnol ; 11: 1229646, 2023.
Article in English | MEDLINE | ID: mdl-38130822

ABSTRACT

Massive irreparable rotator cuff tears (RCTs) affect the clinical outcomes of reverse shoulder arthroplasty (RSA). However, the effects of subscapularis repair on the outcomes of RSA, based on the degree of posterior-superior RCTs, are unclear. This study aimed to examine the effect of subscapularis repair on three-dimensional joint contact forces (JCFs) based on the degree of posterior-superior RCT severity in RSA. Ten human in vivo experimental data were used as input to the musculoskeletal model. A six-degrees-of-freedom (DOF) anatomical shoulder model was developed and validated against three-dimensional JCFs. The 6-DOF musculoskeletal shoulder model of RSA was then developed by importing the reverse shoulder implant into the validated anatomical shoulder model. Based on the various types of posterior-superior RCT severity, inverse dynamic simulations of subscapularis-torn and subscapularis-repaired models of RSA were performed: from isolated supraspinatus tears to partial or massive tears of the infraspinatus and teres minor. The intact rotator cuff model of RSA was also simulated for comparison with the different types of models. Our results showed that the more posterior-superior RCTs progressed in RSA, the more superior JCFs were observed at 90°, 105°, and 120° abduction in the subscapularis-torn model. However, subscapularis repair decreased the superior JCF at those angles sufficiently. In addition, the teres minor muscle-tendon force increased as infraspinatus bundle tears progressed in both the subscapularis-torn and -repaired models, in order to compensate for the reduced force during abduction. However, the teres minor muscle-tendon force was not as high as that of the infraspinatus muscle-tendon, which could result in muscle force imbalance between repaired subscapularis and teres minor. Therefore, our results suggest that repairing the subscapularis and the repairable infraspinatus during RSA can improve glenohumeral joint stability in the superior-inferior direction by restoring muscle force balance between the anterior cuff (i.e., subscapularis) and posterior cuff (i.e., infraspinatus and teres minor). The findings of this study can help clinician decide whether to repair the rotator cuff during RSA to enhance joint stability.

3.
Sci Rep ; 13(1): 20683, 2023 11 24.
Article in English | MEDLINE | ID: mdl-38001172

ABSTRACT

The purpose of this study was to investigate the relationship between muscular parameters of quadriceps/hamstrings and knee joint kinetics in gait. Muscle architecture (thickness, pennation angle, and fascicle length), and quality (echo intensity) of individual quadriceps and hamstrings of 30 healthy participants (16 males and 14 females) was measured using ultrasound. Peak knee flexion moment (KFM), KFM impulse, peak knee adduction moment (KAM), and KAM impulse during walking were obtained at preferred speed. Pearson's correlation coefficient and multiple regression analyses were performed at significance level of 0.05, and Cohen's f2 values were calculated to examine the effect sizes of multiple regression. The hamstring-to-quadriceps muscle thickness ratio (r = 0.373) and semitendinosus echo intensity (r = - 0.371) were predictors of first peak KFM (R2 = 0.294, P = 0.009, f2 = 0.42), whereas only vastus medialis (VM) echo intensity was a significant predictor of second peak KFM (r = 0.517, R2 = 0.267, P = 0.003, f2 = 0.36). Only the VM thickness was the predictor of first (r = 0.504, R2 = 0.254, P = 0.005, f2 = 0.34) and second peak KAM (r = 0.581, R2 = 0.337, P = 0.001, f2 = 0.51), and KAM impulse (r = 0.693, R2 = 0.480, P < 0.001, f2 = 0.92). In conclusion, the greater hamstring-to-quadriceps muscle thickness ratio and the muscle architecture and quality of medial quadriceps/hamstring play an important role in KFM and KAM, and may have implications in knee osteoarthritis.


Subject(s)
Hamstring Muscles , Osteoarthritis, Knee , Male , Female , Humans , Quadriceps Muscle/diagnostic imaging , Hamstring Muscles/diagnostic imaging , Knee Joint/diagnostic imaging , Knee Joint/physiology , Gait/physiology , Knee , Walking/physiology , Biomechanical Phenomena
4.
Sports Health ; 15(4): 519-526, 2023.
Article in English | MEDLINE | ID: mdl-36856193

ABSTRACT

BACKGROUND: Muscle thickness can influence the joint kinematics and/or kinetics during dynamic activities. The relationship between the muscle thickness of individual quadriceps and hamstrings or medial-to-lateral thigh muscle thickness ratio and the knee kinematics/kinetics with respect to anterior cruciate ligament (ACL) injury risk remains unclear. HYPOTHESIS: Higher medial-to-lateral thigh muscle thickness ratio would be associated with lower knee valgus angle/moment and lower tibial internal rotation angle/moment during single-leg landing. STUDY DESIGN: Cross-sectional. LEVEL OF EVIDENCE: Level 4. METHODS: Muscle thickness of the vastus lateralis (VL), vastus medialis (VM), biceps femoris (BF), and semitendinosus (ST) of 30 healthy participants (16 males and 14 females) were measured using ultrasound. Knee joint kinematics and kinetics during single-leg landing were obtained. Stepwise multiple regression analysis, a follow-up Fisher's r to z test to examine the sex as a moderator, and independent t tests to evaluate sex difference were performed. RESULTS: Both knee valgus moment (R2 = 0.466, P < 0.001) and tibial external rotation moment (R2 = 0.330, P < 0.001) at peak anterior tibial shear force during single-leg landing were negatively correlated with medial-to-lateral (ie, (VM+ST):(VL+BF)) thickness ratio regardless of sex, whereas medial-to-lateral thigh muscle thickness ratio was not correlated with knee valgus and tibial external rotation angles. Male participants exhibited higher (VM+ST):(VL+BF) thickness ratio than female participants (P = 0.005), and lower knee valgus moment (P = 0.04) and tibial external rotation moment (P = 0.05), as well. CONCLUSION: The knee joint moments in frontal and transverse planes during single-leg landing were associated with the medial-to-lateral thigh muscle thickness ratio; thus, the medial-lateral thigh muscle thickness could be a potential contributor to frontal and transverse plane knee joint loading during dynamic movement. CLINICAL RELEVANCE: Strength training that aims to selectively strengthen the medial/lateral thigh muscles might be considered in a new ACL injury prevention training program to alter the biomechanical parameters associated with ACL injuries.


Subject(s)
Anterior Cruciate Ligament Injuries , Hamstring Muscles , Female , Male , Humans , Hamstring Muscles/diagnostic imaging , Hamstring Muscles/physiology , Quadriceps Muscle/diagnostic imaging , Leg , Biomechanical Phenomena , Kinetics , Cross-Sectional Studies , Knee Joint
5.
Sci Rep ; 12(1): 18821, 2022 11 05.
Article in English | MEDLINE | ID: mdl-36335259

ABSTRACT

Ankle landing strategies affects the biomechanical characteristics of the knee joint, especially knee frontal plane loading. However, no studies have investigated whether the association between ankle landing biomechanics in sagittal plane and the knee frontal plane loading differs between sexes. The purpose of this study was to examine whether there is a sex difference in the effect of ankle plantar flexion at the contact angle, ankle range of motion (ROM), and ankle plantar flexion moment on knee valgus loading during single-leg landing. Twenty-five females and twenty-four males performed a single-leg landing. Joint kinematics and kinetics of the lower extremities were measured. The relationship between ankle biomechanics in the sagittal plane (ankle plantar flexion angle at contact, ROM, and peak ankle plantar flexion moment) and peak knee valgus moment were analyzed. In males, the larger ankle plantarflexion angle at contact and ROM were significantly associated with lower peak knee valgus moment. In addition, in males only, a greater peak ankle plantar flexion moment was significantly associated with a lower peak knee valgus moment and greater peak ankle inversion moment. Altering ankle landing strategies in the sagittal plane during single-leg landing may reduce the knee valgus moment, which is one of risk factors for anterior cruciate ligament injury, in males only.


Subject(s)
Ankle , Anterior Cruciate Ligament Injuries , Female , Humans , Male , Biomechanical Phenomena , Leg , Sex Characteristics , Knee Joint , Lower Extremity
6.
Front Bioeng Biotechnol ; 10: 851495, 2022.
Article in English | MEDLINE | ID: mdl-35480980

ABSTRACT

The purposes of this study were to develop a cruciate-retaining total knee arthroplasty musculoskeletal model, which enables the adjustment of ligament length and implant alignment; validate the model; and evaluate the effects of varus/valgus alignment adjustment and unbalanced medial/lateral ligament laxity during gait. A cruciate-retaining total knee arthroplasty musculoskeletal model was constructed and validated against the in vivo contact forces. This model was transformed to 2° varus/valgus alignment of femoral or tibial replacement models and 2° medial/lateral laxity models. The contact forces and ligament tensions of the adjusted models were calculated. The contact forces in the model showed good agreement with the in vivo contact forces. Valgus replacement alignment with balanced ligament models showed a lower contact force at the medial compartment than at the neutral alignment model, whereas the varus replacement alignment with balanced ligament models showed a greater contact force at the medial compartment and medial/posterior cruciate ligament tension. The medial laxity with neutral alignment model showed a similar contact force with decreased medial ligament tension compared to the balanced neutral alignment model, whereas the lateral laxity with the neutral alignment model showed a greater contact force and decreased lateral ligament tension. The cruciate-retaining total knee arthroplasty model was validated using in vivo contact forces (r = 0.939) Two degrees of valgus alignment adjustment with balanced ligament or neutral alignment with 2° of medial laxity can be safe without increasing contact force or ligament tension compared to neutral alignment with a balanced extension gap. However, 2° of varus alignment adjustment with balanced ligament or neutral alignment with 2° of lateral laxity may be unfavorable due to the overloading of the joints and knee ligaments.

7.
PLoS One ; 17(2): e0263176, 2022.
Article in English | MEDLINE | ID: mdl-35143528

ABSTRACT

The metatarsophalangeal (MTP) joint is not considered in most current walking assistive devices even though it plays an important role during walking. The purpose of this study was to develop a new MTP assistive device and investigate its effectiveness on the muscle activities of the lower extremities during walking while wearing the device. The MTP assistive device is designed to support MTP flexion by transmitting force through a cable that runs parallel with the plantar fascia. Eight participants were instructed to walk at a constant speed on a treadmill while wearing the device. The muscle activities of their lower extremities and MTP joint kinematics were obtained during walking under both actuated and non-actuated conditions. Paired t-tests were performed to compare the differences in each dependent variable between the two conditions. The muscle activity of the MTP flexor was significantly reduced during walking under actuated conditions (p = 0.013), whereas no differences were found in the muscle activities of other muscles or in the MTP joint angle between actuated and non-actuated conditions (p > 0.05 for all comparisons). In conclusion, the cable-driven MTP assistive device is able to properly assist the MTP flexor without interfering with the action of other muscles in the lower extremities; as such, this MTP assistive device, when integrated into existing exoskeleton designs, has the potential to offer improved walking assistance by reducing the amount of muscle activity needed from the MTP flexor.


Subject(s)
Walking
8.
Sensors (Basel) ; 21(12)2021 Jun 18.
Article in English | MEDLINE | ID: mdl-34207448

ABSTRACT

Classification of terrain is a vital component in giving suitable control to a walking assistive device for the various walking conditions. Although surface electromyography (sEMG) signals have been combined with inputs from other sensors to detect walking intention, no study has yet classified walking environments using sEMG only. Therefore, the purpose of this study is to classify the current walking environment based on the entire sEMG profile gathered from selected muscles in the lower extremities. The muscle activations of selected muscles in the lower extremities were measured in 27 participants while they walked over flat-ground, upstairs, downstairs, uphill, and downhill. An artificial neural network (ANN) was employed to classify these walking environments using the entire sEMG profile recorded for all muscles during the stance phase. The result shows that the ANN was able to classify the current walking environment with high accuracy of 96.3% when using activation from all muscles. When muscle activation from flexor/extensor groups in the knee, ankle, and metatarsophalangeal joints were used individually to classify the environment, the triceps surae muscle activation showed the highest classification accuracy of 88.9%. In conclusion, a current walking environment was classified with high accuracy using an ANN based on only sEMG signals.


Subject(s)
Deep Learning , Walking , Electromyography , Humans , Leg , Muscle, Skeletal
9.
Am J Sports Med ; 49(1): 183-192, 2021 01.
Article in English | MEDLINE | ID: mdl-33381989

ABSTRACT

BACKGROUND: Core stability is influential in the incidence of lower extremity injuries, including anterior cruciate ligament (ACL) injuries, but the effects of core strength training on the risk for ACL injury remain unclear. HYPOTHESIS: Core muscle strength training increases the knee flexion angle, hamstring to quadriceps (H:Q) coactivation ratio, and vastus medialis to vastus lateralis (VM:VL) muscle activation ratio, as well as decreases the hip adduction, knee valgus, and tibial internal rotation angles. STUDY DESIGN: Controlled laboratory study. METHODS: A total of 48 male participants were recruited and randomly assigned to either the intervention group (n = 32) or the control group (n = 16). Three-dimensional trunk, hip, knee, and ankle kinematic data and muscle activations of selected trunk and lower extremity muscles were obtained while the participants performed side-step cutting. The core endurance scores were measured before and after training. Two-way analyses of variance were conducted for each dependent variable to determine the effects of 10 weeks of core strength training. RESULTS: The trunk endurance scores in the intervention group significantly increased after training (P < .05 for all comparisons). The intervention group showed decreased knee valgus (P = .038) and hip adduction angles (P = .032) but increased trunk flexion angle (P = .018), rectus abdominis to erector spinae coactivation ratio (P = .047), H:Q coactivation ratio (P = .021), and VM:VL activation ratio (P = .016). In addition, the knee valgus angle at initial contact was negatively correlated with the VM:VL activation ratio in the precontact phase (R2 = 0.188; P < .001) but was positively correlated with the hip adduction angle (R2 = 0.120; P < .005). No statistically significant differences were observed in the trunk endurance scores, kinematics, and muscle activations for the control group. CONCLUSION: Core strength training altered the motor control strategies and joint kinematics for the trunk and the lower extremity by increasing the trunk flexion angle, VM:VL activation ratio, and H:Q activation ratio and reducing the knee valgus and hip adduction angles. CLINICAL RELEVANCE: Training core muscles can modify the biomechanics associated with ACL injuries in a side-step cutting task; thus, core strength training might be considered in ACL injury prevention programs to alter the lower extremity alignment in the frontal plane and muscle activations during sports-related tasks.


Subject(s)
Abdominal Muscles/physiology , Anterior Cruciate Ligament Injuries/therapy , Lower Extremity/physiology , Resistance Training , Torso/physiology , Adult , Anterior Cruciate Ligament Injuries/prevention & control , Biomechanical Phenomena , Humans , Knee Joint , Male , Range of Motion, Articular , Risk Factors
10.
Gait Posture ; 83: 127-131, 2021 01.
Article in English | MEDLINE | ID: mdl-33130387

ABSTRACT

BACKGROUND: Increasing the ankle plantar-flexion angle at initial contact (IC) during landing reduces the impact features associated with landing, such as the vertical ground reaction force and loading rate, potentially affecting the risk of anterior cruciate ligament (ACL) injury. However, the relationships between the ankle plantar-flexion angle at IC and the previously identified biomechanical factors related to noncontact ACL injury have not been studied. RESEARCH QUESTION: Thus, the purpose of this study was to determine whether significant relationships exist between the ankle plantar-flexion angle at IC and the biomechanical factors related to noncontact ACL injury. METHODS: The peak anterior tibial shear force, peak external knee valgus moment, peak knee valgus angle, and combined peak external knee valgus plus tibial internal rotation moments were measured in 26 individuals while performing self-selected, single-leg landing. Pearson correlation analyses were performed to assess the relationships between the ankle plantar-flexion angle at IC and the biomechanical factors mentioned above. RESULTS: The greater ankle plantar-flexion angle at IC was related to smaller the peak knee valgus moment (r = -0.5, p = 0.009) and the combined peak knee valgus plus internal rotation moments (r = -0.58, p = 0.001). SIGNIFICANCE: These results suggest that large ankle plantar-flexion angle at IC might be associated with lesser loading of the knee frontal plane and altering the self-selective ankle angle may result in biomechanical changes associated with ACL injury risk.


Subject(s)
Ankle/physiopathology , Anterior Cruciate Ligament Injuries/physiopathology , Biomechanical Phenomena/physiology , Adult , Humans , Male , Risk Factors , Young Adult
11.
J Mot Behav ; 52(6): 703-712, 2020.
Article in English | MEDLINE | ID: mdl-31679474

ABSTRACT

The objective of this study was to examine the effects of muscle strength training on knee kinematics/kinetics and muscle activation patterns during anticipated side-step cutting. Three-dimensional knee kinematics/kinetics data and muscle activation of selected lower extremity muscles were measured while performing cutting before and after completing 10-week circuit strength training mixed typical resistance training and power training (intervention) or no training (control) from 25 female subjects. The muscle strength of quadriceps and hamstrings were measured before and after training using isokinetic dynamometer. No statistically significant differences were observed in quadriceps and hamstrings muscle strength, all kinematic/kinetic variables, and muscle activation for the control group. Both quadriceps (p = 0.005) and hamstrings (p = 0.030) muscle strength were increased after training. An increased biceps femoris (p = 0.003) and H:Q ratio of activation (p = 0.016), as well as decreased gastrocnemius muscle activation (p = 0.012) during pre-activation phase in intervention group were found. No significant differences were found in knee kinematics and kinetics both at the time frame of the initial contact and the peak tibial anterior shear force after training. In conclusion, muscle strength training altered some muscle activations of lower extremity muscles, which might affect the risk of ACL injury, but it did not change the kinematic/kinetic parameters.


Subject(s)
Knee Joint/physiology , Lower Extremity/physiology , Muscle Strength/physiology , Muscle, Skeletal/physiology , Resistance Training , Adult , Biomechanical Phenomena/physiology , Electromyography , Female , Humans , Knee/physiology , Young Adult
12.
Biomech Model Mechanobiol ; 18(2): 479-489, 2019 Apr.
Article in English | MEDLINE | ID: mdl-30474763

ABSTRACT

Damage to the acetabular labrum has been associated with cartilage degeneration. Because conventional pressure measurement devices were unable to examine the sealing function of the acetabular labrum on cartilage contact mechanics, we used an image-based computational method to examine how labrectomy affects articular cartilage contact area and strain patterns in porcine hips. Cyclically loaded hip samples were continuously imaged in a CT scanner every 3 min to trace the positions of the femur and acetabulum. Image-based displacement-controlled finite element analysis was used to calculate articular cartilage contact area and nominal strain at different time points. No changes in cartilage contact area were found after labrectomy. Compared to the labrum intact condition, average nominal strain in labrectomized hips was elevated at early time points after load application. The areas of 'high' strain in labrectomized hips were found to be increased by approximately 7% after 30 min of cyclic loading, while the changes in the areas of 'low' strain were minimal. Our result showed that changes in articular cartilage strain following labrectomy were concentrated on locally overloaded areas where the degenerative process of articular cartilage may be initiated.


Subject(s)
Acetabulum/anatomy & histology , Cartilage, Articular/anatomy & histology , Acetabulum/diagnostic imaging , Acetabulum/surgery , Animals , Cartilage, Articular/diagnostic imaging , Femur/anatomy & histology , Femur/diagnostic imaging , Finite Element Analysis , Image Processing, Computer-Assisted , Imaging, Three-Dimensional , Joints/anatomy & histology , Joints/diagnostic imaging , Pelvis/anatomy & histology , Pelvis/diagnostic imaging , Pressure , Swine , Time Factors , Tomography, X-Ray Computed
13.
IEEE Trans Biomed Eng ; 66(6): 1609-1617, 2019 06.
Article in English | MEDLINE | ID: mdl-30334746

ABSTRACT

Residual hearing loss in cochlear implant users is investigated using the mechanical-human-cochlear model. Hearing loss due to stiffening of the round window increases significantly as input frequencies decrease from 3 kHz to 1 kHz but remains constant at lower frequencies, whereas loss due to the presence of an electrode insert becomes significantly higher at lower frequencies ([Formula: see text] kHz). The latter also shifts the characteristic frequency map toward the basal end of the cochlea. In the region away from the end of the electrode insert, cochlear function recovers, but the user still suffers from hearing loss caused by round window stiffening.


Subject(s)
Cochlear Implants/adverse effects , Hearing Disorders/physiopathology , Round Window, Ear/physiopathology , Speech Perception/physiology , Acoustic Stimulation/instrumentation , Basilar Membrane/physiopathology , Hearing/physiology , Hearing Disorders/surgery , Humans , Models, Biological , Signal Processing, Computer-Assisted
14.
Appl Bionics Biomech ; 2018: 2028638, 2018.
Article in English | MEDLINE | ID: mdl-30018660

ABSTRACT

During continuous uphill walking (UW) or downhill walking, human locomotion is modified to counteract the gravitational force, aiding or impeding the body's forward momentum, respectively. This study aimed at investigating the center of mass (COM) and center of pressure (COP) velocities and their relative distance during the transition from uphill to downhill walking (UDW) to determine whether locomotor adjustments differ between UDW and UW. Fourteen participants walked on a triangular slope and a continuous upslope of 15°. The kinematics and COPs were obtained using a force plate and a motion capture system. The vertical velocity of the COM in the propulsion phase, the horizontal distance between the COM and COP at initial contact, and the duration of the subphases significantly differed between UDW and UW (all p < 0.05). Compared with the results of UW, longer durations and the deeper downward moving COM in the propulsion phase were observed during UDW (all p < 0.05). Additionally, a shorter horizontal distance between the COM and COP at initial contact was associated with a slower vertical COM velocity in the propulsion phase during UDW. The reduced velocity is likely a gait alteration to decrease the forward momentum of the body during UDW.

15.
Gait Posture ; 62: 99-104, 2018 05.
Article in English | MEDLINE | ID: mdl-29544157

ABSTRACT

BACKGROUND: During landing, the ankle angle at initial contact (IC) exhibits relatively wide individual variation compared to the knee and hip angles. However, little is known about the effect of different IC ankle angles on energy dissipation. RESEARCH QUESTION: The purpose of this study was to investigate the relationship between individual ankle angles at IC and energy dissipation in the lower extremity joints. METHODS: Twenty-seven adults performed single-leg landings from a 0.3-m height. Kinetics and kinematics of the lower extremity joints were measured. The relationship between ankle angles at IC and negative work, range of motion, the time to peak ground reaction force, and peak loading rate were analyzed. RESULTS: The ankle angle at IC was positively correlated with ankle negative work (r = 0.80, R2 = 0.64, p < 0.001) and the contribution of the ankle to total (ankle, knee and hip joint) negative work (r = 0.84, R2 = 0.70, p < 0.001), but the ankle angle was negatively correlated with hip negative work (r = -0.46, R2 = 0.21, p = 0.01) and the contribution of the hip to total negative work (r = -0.61, R2 = 0.37, p < 0.001). The knee negative work and the contribution of the knee to total negative work were not correlated with the ankle angle at IC. The ankle angle at IC was positively correlated with total negative work (r = 0.50, R2 = 0.25, p < 0.01) and negatively correlated with the peak loading rate (r = -0.76, R2 = 0.57, p < 0.001). SIGNIFICANCE: These results indicated that landing mechanics changed as the ankle angle at IC increased, such that the ankle energy dissipation increased and redistributed the energy dissipation in the ankle and hip joints. Further, these results suggest that increased ankle energy dissipation with a higher IC plantar flexion angle may be a potential landing technique for reducing the risk of injury to the anterior cruciate ligament and hip musculature.


Subject(s)
Ankle Joint/physiology , Hip Joint/physiology , Knee Joint/physiology , Lower Extremity/physiology , Movement/physiology , Range of Motion, Articular/physiology , Anterior Cruciate Ligament/physiology , Female , Healthy Volunteers , Humans , Male , Young Adult
16.
Clin Biomech (Bristol, Avon) ; 53: 1-6, 2018 03.
Article in English | MEDLINE | ID: mdl-29407350

ABSTRACT

BACKGROUND: It has been generally speculated that paraspinal muscle weakness is related to the spinal degeneration including intervertebral disc failure. The purpose of this study was to investigate the effects of paraspinal muscle weakness induced by the botulinum toxin type-A on the lumbar spine and behavior pattern in an in-vivo primate model which has an upright locomotion similar to that of humans. METHODS: Botox injections into paraspinal muscle of one cynomolgus monkey were conducted biweekly up to 19 weeks at L2-L3, L3-L4 and L4-L5. MRIs were performed for measurement of muscle cross-sectional areas and behavioral data were collected using a high-resolution portable digital video camera. FINDINGS: The cross-sectional areas of the paraspinal muscles at L2-L3, L3-L4 and L4-L5 decreased by 8%, 12% and 8% at 21 weeks after the Botox injection, respectively. Intervertebral disc thickness at L2-L3, L3-L4 and L4-L5 decreased by 6%, 8% and 5% at 21 weeks after initial Botox injection, respectively. After the Botox injections, locomotion and movement activity of the monkey was decreased. The duration of sitting increased from 21% to a maximum of 97% at 9 weeks after the Botox injection, while stance time decreased from 9% to a minimum of 1% at 11 weeks post Botox injection. INTERPRETATION: The findings of this study revealed that paraspinal muscle atrophy affects intervertebral disc morphology and locomotion activity of a primate and may lead to an onset of intervertebral disc degeneration.


Subject(s)
Botulinum Toxins, Type A/adverse effects , Locomotion/physiology , Lumbar Vertebrae/physiopathology , Motor Activity/physiology , Muscle Weakness/chemically induced , Neuromuscular Agents/adverse effects , Paraspinal Muscles/drug effects , Animals , Cross-Sectional Studies , Disease Models, Animal , Female , Humans , Intervertebral Disc Degeneration/diagnostic imaging , Intervertebral Disc Degeneration/physiopathology , Lumbar Vertebrae/diagnostic imaging , Macaca fascicularis , Magnetic Resonance Imaging , Male , Middle Aged , Muscle Weakness/diagnostic imaging , Muscle Weakness/physiopathology , Muscular Atrophy/physiopathology , Paraspinal Muscles/diagnostic imaging
17.
IEEE Trans Biomed Eng ; 65(5): 980-988, 2018 05.
Article in English | MEDLINE | ID: mdl-28767362

ABSTRACT

Although the stretch reflex plays an important role in spasticity, so far the stretch reflex has not been sufficiently investigated. Previous stretch reflex activation models have some limitations, whereby they are not able to predict outcomes of some stretch reflex cases and do not consider uneven distribution of muscle length and stretch velocity on reflex activation. The purpose of this study was: 1) to develop a modified stretch reflex activation model employing a new muscle length threshold and weighting factors for slow-twitch fiber and fast-twitch fiber, and 2) to validate the model using pendulum experiments of the lower and upper limbs. The new muscle length threshold was defined using the optimal muscle fiber length. Based on the optimal fiber length, the new threshold allows for prediction of the stretch reflex activation at muscle lengths shorter than have been possible with previous models. The muscle type weighting factors realized unequal contributions between the muscle length and stretch velocity. We proved the validity of the proposed reflex activation model by using pendulum tests to induce patellar tendon and biceps brachii reflexes. Unknown parameters employed in the proposed model were obtained by minimizing differences in motion obtained with the proposed model and experiments. The proposed model can predict stretch reflex activation at shorter muscle lengths. In addition, the proposed model reflected nonhomogeneous characteristics related to the unequal contributions between muscle length and stretch velocity. As a result, patellar tendon and biceps brachii reflex phenomena were shown to be predicted more accurately in this study.


Subject(s)
Models, Biological , Muscle, Skeletal/physiology , Reflex, Stretch/physiology , Adult , Arm/physiology , Electromyography , Humans , Leg/physiology , Male , Muscle Contraction/physiology , Muscle Fibers, Fast-Twitch/physiology , Muscle Fibers, Slow-Twitch/physiology , Muscle Spasticity/physiopathology , Young Adult
18.
J Appl Biomech ; 33(6): 397-405, 2017 Dec 01.
Article in English | MEDLINE | ID: mdl-28530482

ABSTRACT

The purpose of this study was to investigate the effect of load carriage on the kinematics and kinetics of the ankle and knee joints during uphill walking, including joint work, range of motion (ROM), and stance time. Fourteen males walked at a self-selected speed on an uphill (15°) slope wearing military boots and carrying a rifle in hand without a backpack (control condition) and with a backpack. The results showed that the stance time significantly decreased with backpack carriage (p < .05). The mediolateral impulse significantly increased with backpack carriage (p < .05). In the ankle joints, the inversion-eversion, and dorsi-plantar flexion ROM in the ankle joints increased with backpack carriage (p < .05). The greater dorsi-plantar flexion ROM with backpack carriage suggested 1 strategy for obtaining high plantar flexor power during uphill walking. The result of the increased mediolateral impulse and inversion-eversion ROM in the ankle joints indicated an increase in body instability caused by an elevated center of mass with backpack carriage during uphill walking. The decreased stance time indicated that an increase in walking speed could be a compensatory mechanism for reducing the instability of the body during uphill walking while carrying a heavy backpack.


Subject(s)
Ankle Joint/physiology , Knee Joint/physiology , Walking/physiology , Weight-Bearing/physiology , Biomechanical Phenomena , Humans , Kinetics , Male , Military Personnel , Range of Motion, Articular/physiology , Young Adult
19.
Hear Res ; 345: 1-9, 2017 03.
Article in English | MEDLINE | ID: mdl-27986594

ABSTRACT

The frequency selectivity of a gerbil cochlea, unlike other mammals, does not depend on varying thickness and width of its basilar membrane from the basal to the apical end. We model the gerbil arched basilar membrane focusing on the radial tension, embedded fiber thickness, and the membrane arch, which replace the functionality of the variation in thickness and width. The model is verified with the previous gerbil cochlea model which estimated the equivalent basilar membrane thickness and is shown to be more accurate than the flat sandwiched basilar membrane model. The simple sinusoidal-shaped bending mode assumption in previous models is found to be valid in the present model with <12% error. Parametric study on the present model shows that fiber thickness contribution to the membrane stiffness is close to the 3rd order, higher than the 1st order estimation of previous models. We found that the effective Young's modulus of the fiber bundle is at least 6 orders higher than the shear modulus of the soft-cells and the membrane radial bending stiffness is more sensitive to the membrane arch and the shear modulus of the soft-cells near the apical end.


Subject(s)
Basilar Membrane/physiology , Cochlea/physiology , Hearing , Models, Biological , Animals , Basilar Membrane/anatomy & histology , Biomechanical Phenomena , Cochlea/anatomy & histology , Computer Simulation , Elastic Modulus , Gerbillinae , Mechanotransduction, Cellular , Pressure , Stress, Mechanical
20.
Gait Posture ; 48: 89-94, 2016 07.
Article in English | MEDLINE | ID: mdl-27477715

ABSTRACT

The mid-foot contact area relative to the total foot contact area can facilitate foot arch structure evaluation. A stair descent motion consistently provides initial fore-foot contact and utilizes the foot arch more actively for energy absorption. The purpose of this study was to compare ankle and knee joint angle, moment, and work in sagittal plane during stair descending between low and high Mid-Foot-Contact-Area (MFCA) ratio group. The twenty-two female subjects were tested and classified into two groups (high MFCA and low MFCA) using their static MFCA ratios. The ground reaction force (GRF) and kinematics of ankle and knee joints were measured while stair descending. During the period between initial contact and the first peak in vertical GRF (early absorption phase), ankle negative work for the low MFCA ratio group was 33% higher than that for the high MFCA ratio group (p<0.05). However, ankle negative work was not significantly different between the two groups during the period between initial contact and peak dorsiflexion angle (early absorption phase+late absorption phase). The peak ankle dorsiflexion angle was smaller in the low MFCA ratio group (p<0.05). Our results suggest that strategy of energy absorption at the ankle and foot differs depending upon foot arch types classified by MFCA. The low MFCA ratio group seemed to absorb more impact energy using strain in the planar fascia during early absorption phase, whereas the high MFCA ratio group absorbed more impact energy using increased dorsiflexion during late absorption phase.


Subject(s)
Ankle Joint/physiology , Foot/physiology , Knee Joint/physiology , Locomotion/physiology , Adult , Biomechanical Phenomena/physiology , Female , Humans , Kinetics , Young Adult
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