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Prenat Diagn ; 40(7): 885-891, 2020 06.
Article in English | MEDLINE | ID: mdl-32281112

ABSTRACT

OBJECTIVE: To report our experience and evaluate outcomes in monochorionic pregnancies with Twin Reversed Arterial Perfusion sequence with intrafetal laser therapy. METHODS: Retrospective review of records of all pregnancies with TRAP sequence treated by intrafetal laser therapy between 2011 January and 2015 December that were retrieved and analysed. RESULTS: Electronic search of the scan database retrieved 57 cases of TRAP sequence during the study period, 7 triplets and 50 monochorionic twins. Intrafetal laser was done in 27 cases, 22 cases of twins and 5 cases of triplets. In the twins group, median gestational age at intervention was 22.5 weeks, the earliest done at 16.3 weeks. The median gestational age at delivery and birth weight was 37 weeks and 2.5 Kgs. The median procedure and delivery interval was 14 weeks. Live birth rate was 17/22 (77%) the pump survival rate was 16/22 (73%). Pregnancies with non-surviving pump were 5 in numbers (5/22). A repeat procedure was warranted in one case. In the triplet group, median gestational age at intervention, delivery and procedure delivery interval was 18, 35 and 17 weeks. CONCLUSION: Intrafetal laser is simple, effective and the treatment of choice to interrupt the vascular supply to acardiac twin.


Subject(s)
Fetofetal Transfusion/surgery , Fetoscopy , Laser Therapy/methods , Pregnancy Trimester, Second , Adult , Diseases in Twins/diagnosis , Diseases in Twins/epidemiology , Diseases in Twins/surgery , Female , Fetofetal Transfusion/diagnosis , Fetofetal Transfusion/epidemiology , Fetoscopy/adverse effects , Fetoscopy/mortality , Fetoscopy/statistics & numerical data , Gestational Age , Humans , India/epidemiology , Infant, Newborn , Laser Therapy/adverse effects , Laser Therapy/mortality , Laser Therapy/statistics & numerical data , Male , Pregnancy , Pregnancy Outcome/epidemiology , Pregnancy Reduction, Multifetal/adverse effects , Pregnancy Reduction, Multifetal/methods , Pregnancy Reduction, Multifetal/mortality , Pregnancy Reduction, Multifetal/statistics & numerical data , Pregnancy, Twin/statistics & numerical data , Retrospective Studies , Survival Rate , Treatment Outcome , Triplets/statistics & numerical data , Twins/statistics & numerical data
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