1.
Org Lett
; 4(10): 1691-4, 2002 May 16.
Article
in English
| MEDLINE
| ID: mdl-12000275
ABSTRACT
[reaction: see text] The PdCl2(PPh3)2-catalyzed Sonogashira coupling reaction, in good to high yields, was performed in an ionic liquid ([BMIm][PF6]) in the absence of a copper salt. The use of an ionic liquid allows for the facile separation and recycling of the catalyst. The application of the above reaction in a microflow system in conjunction with an IMM micromixer was also successful.