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1.
Sleep Med Clin ; 14(1): 41-50, 2019 Mar.
Article in English | MEDLINE | ID: mdl-30709532

ABSTRACT

The role of the nose in the pathophysiology and treatment of sleep-disordered breathing (SDB) has not been fully understood and might have been underestimated. In the Staring resistor model, the nose is regarded as a passive and noncollapsible tube, but recent studies have shown that the nose might participate more in the pathophysiology of SDB as anatomic, neuromuscular, and respiratory factors than previously reported, which might imply the nose is an active noncollapsible tube. The roles of nasal treatments for OSA are not only the reduction of AHI, but also the improvement of subjective symptoms, sleep quality, and CPAP adherence.


Subject(s)
Nasal Cavity/surgery , Sleep Apnea Syndromes/surgery , Humans , Sleep Apnea, Obstructive , Treatment Outcome
2.
JSLS ; 17(2): 346-9, 2013.
Article in English | MEDLINE | ID: mdl-23925035

ABSTRACT

BACKGROUND: We report a rare case of malignant hyperthermia during laparoscopic adjustable gastric banding. CASE DESCRIPTION: A 32-y-old female with no previous history of adverse reaction to general anesthesia underwent laparoscopic adjustable gastric banding. Intraoperative monitoring revealed a sharp increase in end-tidal carbon dioxide, autonomic instability, and metabolic and respiratory acidosis, along with other metabolic and biochemical derangements. She was diagnosed with malignant hyperthermia. Desflurane, the anesthetic agent was discontinued, and the patient was started on intravenous dantrolene. RESULTS: The surgery was completed, and the patient was brought to the surgical intensive care unit for continued postoperative care. She developed muscle weakness and phlebitis that resolved prior to discharge. CONCLUSION: Prompt diagnosis and treatment of malignant hyperthermia leads to favorable clinical outcome. This clinical entity can occur in the bariatric population with the widely used desflurane. Bariatric surgeons and anesthesiologists alike must be aware of the early clinical signs of this rare, yet potentially fatal, complication.


Subject(s)
Gastroplasty/adverse effects , Gastroplasty/methods , Laparoscopy/adverse effects , Malignant Hyperthermia/etiology , Adult , Anesthetics, Inhalation/adverse effects , Comorbidity , Desflurane , Female , Humans , Isoflurane/adverse effects , Isoflurane/analogs & derivatives , Malignant Hyperthermia/epidemiology , Malignant Hyperthermia/physiopathology , Obesity, Morbid/epidemiology , Obesity, Morbid/surgery
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