ABSTRACT
A 63-year-old man was admitted to a hospital owing to shortness of breath. He was diagnosed as having gastric cancer with pulmonary carcinomatous lymphangitis(PCL)and disseminated carcinomatosis of the bone marrow(DCBM). Regarding tumor markers, carcinoembryonic antigen(CEA)and carbohydrate antigen 19-9(CA19-9)levels increased to 332 ng/ mL and 921 U/mL, respectively. Since the disease was also accompanied by disseminated intravascular coagulation(DIC), S- 1 plus cisplatin chemotherapy was started immediately(S-1 120 mg/body administered for 21 days and cisplatin 60 mg/m2 administered on day 8, 35 days for a course). Approximately 2 weeks after the initiation of chemotherapy, the patient's respiratory symptoms improved, and he recovered from DIC. After 2 chemotherapy courses, tumor marker levels decreased (CEA 9.3 ng/mL and CA19-9 314 U/mL), and the patient continued to receive chemotherapy without the deterioration of his physical condition for 5 months. However, he experienced fatigue after 4 courses, because of the progression of gastric cancer. Although the regimen was changed to ramucirumab plus paclitaxel chemotherapy, the patient died 8 months after the initiation of chemotherapy. An accumulation of cases is needed to establish treatment strategies for gastric cancer with PCL and/or DCBM.
Subject(s)
Carcinoma , Lung Neoplasms , Lymphangitis , Peritoneal Neoplasms , Stomach Neoplasms , Male , Humans , Middle Aged , Cisplatin , Stomach Neoplasms/complications , Stomach Neoplasms/drug therapy , Carcinoembryonic Antigen , Bone Marrow , CA-19-9 Antigen , Lymphangitis/drug therapy , Lymphangitis/etiology , Lung Neoplasms/drug therapy , Drug CombinationsABSTRACT
Although oophorectomy for ovarian metastasis from colorectal cancer is encouraged to improve the prognosis, that is also performed to relieve the symptom such as abdominal distention. We report a surgical case of intestinal obstruction due to ovarian metastasis after ileocecal resection for cecal cancer diagnosed at 77 years old.
Subject(s)
Anticoagulants/administration & dosage , Blood Coagulation/drug effects , Heparin/administration & dosage , Vena Cava, Inferior , Venous Thrombosis/drug therapy , Warfarin/administration & dosage , Aged , Female , Humans , Treatment Outcome , Vena Cava, Inferior/diagnostic imaging , Venous Thrombosis/diagnostic imagingSubject(s)
Aneurysm, Infected/complications , Aortic Aneurysm, Abdominal/complications , Aortic Rupture/etiology , Duodenal Diseases/etiology , Intestinal Fistula/etiology , Vascular Fistula/etiology , Aged, 80 and over , Aneurysm, Infected/diagnostic imaging , Aneurysm, Infected/surgery , Aortic Aneurysm, Abdominal/diagnostic imaging , Aortic Aneurysm, Abdominal/surgery , Aortic Rupture/prevention & control , Aortography/methods , Blood Vessel Prosthesis Implantation , Computed Tomography Angiography , Duodenal Diseases/diagnostic imaging , Duodenal Diseases/surgery , Fatal Outcome , Humans , Intestinal Fistula/diagnostic imaging , Intestinal Fistula/surgery , Male , Recurrence , Suture Techniques , Treatment Outcome , Vascular Fistula/diagnostic imaging , Vascular Fistula/surgeryABSTRACT
Nontyphoidal salmonellosis has a wide variety of clinical presentations. With the aim of describing the detailed clinical presentations of gastroenteritis caused by nontyphoidal Salmonella spp., findings for 126 patients (1-94 years of age; 37.0 years on average) were analyzed. Nontyphoidal salmonellosis is prevalent from April to October in Akita, when the mean atmospheric temperature exceeds 10 degrees C. On physical examination, 3 patients had rebound tenderness and muscle guarding on their abdominal wall; 1 of these patients underwent surgery for associated acute appendicitis. Elderly patients tended to be more seriously affected, resulting in severe dehydration. Elevation of the serum C-reactive protein (CRP) level correlated well with a decline in the platelet count. Although nontyphoidal salmonellosis is a common cause of acute gastroenteritis, thorough investigation and meticulous care are required so that conditions requiring surgical treatment or those that are potentially fatal are not overlooked.
