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Transplant Proc ; 44(8): 2397-8, 2012 Oct.
Article in English | MEDLINE | ID: mdl-23026604

ABSTRACT

INTRODUCTION: Some special situations may require aortic clamping during pancreas transplantation (PT). The most important problem is ischemic injury to a previous transplanted kidney. We sought to demonstrate experience with aortic clamping in PT without special kidney allograft protection measures and its impact on kidney function. METHODS: Retrospective study that analyzed 6 patients who underwent PT (5 pancreas after kidney and 1 simultaneous pancreas-kidney) with aortic clamping. In all cases, the pancreas graft was placed on the right with retrocolic portal-enteric drainage. Serum creatinine was evaluated pre- and posttransplantation. RESULTS: The average clamping time was 19 minutes. The mean serum creatinine was 1.1, 1.15, 0.95, and 1.0, respectively, at pre and postoperative days 1 and 7 and at hospital discharge. Patient, kidney, and pancreatic graft survivals were 100%, 100%, and 83%, respectively. CONCLUSION: The need for aortic clamping in selected cases of PT did not seem to affect the transplanted kidney, even without protective measures, provided that the ischemic time was short.


Subject(s)
Aorta/surgery , Kidney Transplantation , Pancreas Transplantation/methods , Vascular Surgical Procedures , Adult , Biomarkers/blood , Constriction , Creatinine/blood , Female , Graft Survival , Humans , Kidney Transplantation/adverse effects , Male , Middle Aged , Pancreas Transplantation/adverse effects , Retrospective Studies , Time Factors , Treatment Outcome , Vascular Surgical Procedures/adverse effects , Warm Ischemia
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