1.
Org Lett
; 17(8): 1922-5, 2015 Apr 17.
Article
in English
| MEDLINE
| ID: mdl-25823962
ABSTRACT
A set of novel SO2-containing azabicyclo[3.n.1]alkanes has been synthesized by the double-Mannich annulation of of the corresponding monocyclic S-ketones. These compounds have been rationally designed as 3D-shaped, conformationally restricted SO2-containing building blocks for drug discovery.