[The use of verapamil in suppositories for treating patients with ischemic heart disease]. / Primenenie verapamila v svechakh dlia lecheniia bol'nykh ishemicheskoi bolezn'iu serdtsa.

A study is presented of 51 patients with ischemic heart disease showing stenocardia of functional classes II-III. The patients received verapamil in suppositories. Cessation or reduced of the frequency of stenocardia attacks were noted after a 10-day course of verapamil (dose--40 mg 3 times daily) in 98.1% of patients. The effect of verapamil treatment was more pronounced in angina pectoris without myocardial infarction in the anamnesis. In IHD patients arterial pressure reduced due to decrease of the general peripheral resistance while the cardiac ejection remained unchanged. The antiarrhythmic effect was more pronounced in atrial extrasystole. Side-effects due to verapamil treatment were not registered.