The consequences of COVID-19 and its vaccine on pregnant and lactating mothers.

The single-stranded RNA virus (coronavirus 2019) pandemic has represented a massive influence on health care professionals and communities around the world. This virus is accompanied by a range of respiratory disorders. Morbidity and mortality are in elevation among pregnant mothers. COVID-19 vaccine is considered safe for the majority of the population. Safety concerns were raised toward pregnant mothers and the COVID-19 vaccine. In the present study, data were taken out from relevant manuscripts; from 20th April 2021 to 25th December 2021. In this study, literature reviews from the most comprehensive health database on 100 papers published during 2020 and 2021 were used. This review article aimed to assess the present evidence available in the literature about the possible effect of COVID-19 on pregnant mothers and their fetuses and, to address considerations for maternal COVID-19 vaccine based on the review of existing data to aid in spreading the awareness about the benefits of vaccine that could save lives. In general, COVID-19 vaccines resulted in reducing the ability of virus transmission and patients' hospitalization. COVID-19 vaccines will never cause infection of corona virus. Evidence showed that COVID-19 vaccines from any brand will reduce the mortality and morbidity. However, available data indicated that possible deterioration of the clinical conditions of pregnant mothers infected with COVID-19 cannot be excluded. Primary outcomes did not show clear safety signs among pregnant mothers who received COVID-19 vaccines. This is because pregnant and lactating mothers were excluded from COVID-19 vaccine studies. Thus, data to lead vaccine decision-making are inadequate. More longitudinal follow up studies are necessary to reinforce the safety of the vaccine.

Scroto-perineal hidradenitis suppurativa complicated by giant scrotal elephantiasis.

Scrotal elephantiasis has been a recognized complication of inguinal node irradiation, filarial infection, tumor involvement and surgical lymphatic destruction, but has rarely been reported in association with hidradenitis suppurativa (HS). HS, also known as acne inversa, is a chronic and often debilitating disease primarily affecting the axillae, inframammary regions and perineum. The location of the lesions may lead to social embarrassment and failure to seek medical treatment. Scroto-preineal HS complicated by scrotal elephantiasis is a distressing disease. Excisional surgery with reconstruction is the recommended treatment with a high likelihood of good outcome. We present a 38-year-old male patient with long-standing scroto-perineal HS complicated by giant scrotal elephantiasis.