[APPLICATION OF ALLOGENIC TISSUE OF THE FETAL BRAIN CORTEX AND THE OLFACTORY BULB TISSUE FOR TREATMENT OF THE BRAIN CONTUSION IN RATS].

Impact of the allogenic tissue transplantation of the fetal cerebral large hemispheres and the оlfactory bulb tissue (OBT) on the healing processes after the brain contusion was studied in experiment. The investigation was performed on mongrel male rats: in laboratory animals of the first group in the first day after open penetrating local cerebral trauma (OPLCT) the allogenic fetal nervous tissue fragment was transplanted into the formatted tissue defect; for the second group ­ in the first day after cerebral trauma the allogenic OBT fragment was transplanted into the formatted tissue defect; and for the third group (control) - the OPLCT was done without further transplantation of tissues. The impact of the allogenic fetal nervous tissue transplantation was demonstrated by more active participation of glial cells during the healing process course, and the OBT transplantation was followed by activation of neoangiogenesis processes , mainly in the injured brain. The experimental simulation choosed permits to study the possibilities of application of neurogenic tissues in the brain contusion treatment, and to determine the therapy tactics.

[Seasonal changes in several ultrastructural indices of lake frog heart ventricle myocytes]. / Sezonnye izmeneniia nekotorykh ul'trastrukturnykh pokazatelei miotsitov zheludochnka serdtsa ozernoi liagushki

The method of electron microscopy with morphometric analysis was applied to the study of some ultrastructural indices of frog heart (ventricle) myocardium - the interlocated discs, the lateral junctions and mitochondria - in spring and in autumn. The results obtained pointed to seasonal differences in the cardiomyocyte ultrastructure, this being confirmed by the quantitative analysis.